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EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31124-7
By:
- Bhatia, Shilpa;
- Nguyen, Diemmy;
- Darragh, Laurel B.;
- Van Court, Benjamin;
- Sharma, Jaspreet;
- Knitz, Michael W.;
- Piper, Miles;
- Bukkapatnam, Sanjana;
- Gadwa, Jacob;
- Bickett, Thomas E.;
- Bhuvane, Shiv;
- Corbo, Sophia;
- Wu, Brian;
- Lee, Yichien;
- Fujita, Mayumi;
- Joshi, Molishree;
- Heasley, Lynn E.;
- Ferris, Robert L.;
- Rodriguez, Olga;
- Albanese, Christopher
Publication type:
Article
Signalling in stem cells.
Published in:
2004
By:
- Heasley, Lynn E.;
- Petersen, Bryon E.
Publication type:
Report
Concise Review: Regulation of Embryonic Stem Cell Lineage Commitment by Mitogen-Activated Protein Kinases.
Published in:
Stem Cells, 2007, v. 25, n. 5, p. 1090, doi. 10.1634/stemcells.2006-0612
By:
- BINÉTRUY, BERNARD;
- HEASLEY, LYNN;
- BOST, FRÉDÉRIC;
- CARON, LESLIE;
- AOUADI, MYRIAM
Publication type:
Article
Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib.
Published in:
2019
By:
- Ng, Terry L.;
- Yu, Hui;
- Smith, Derek E.;
- Boyle, Theresa A.;
- York, Emily R.;
- Leedy, Scott;
- Gao, Dexiang;
- Aisner, Dara L.;
- Van Bokhoven, Adrie;
- Heasley, Lynn E.;
- Hirsch, Fred R.;
- Camidge, D. Ross
Publication type:
journal article
A miRNA Panel Predicts Sensitivity of FGFR Inhibitor in Lung Cancer Cell Lines.
Published in:
2018
By:
- Shengxiang Ren;
- Rivard, Christopher J.;
- Hui Yu;
- Genova, Carlo;
- Rozenboom, Leslie;
- Dexiang Gao;
- Hinz, Trista K.;
- Rikke, Brad A.;
- Wynes, Murry W.;
- Caldwell, Charles;
- Agustoni, Francesco;
- Kenichi suda;
- Tao Jiang;
- Caicun Zhou;
- Heasley, Lynn E.;
- Hirsch, Fred R.;
- Ren, Shengxiang;
- Yu, Hui;
- Gao, Dexiang;
- Jiang, Tao
Publication type:
journal article
An Inducible TGF-β2-TGFβR Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases.
Published in:
PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0123600
By:
- Kleczko, Emily K.;
- Kim, Jihye;
- Keysar, Stephen B.;
- Heasley, Lydia R.;
- Eagles, Justin R.;
- Simon, Matthew;
- Marshall, Marianne E.;
- Singleton, Katherine R.;
- Jimeno, Antonio;
- Tan, Aik-Choon;
- Heasley, Lynn E.
Publication type:
Article
Resistance to ROS1 Inhibition Mediated by EGFR Pathway Activation in Non-Small Cell Lung Cancer.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082236
By:
- Davies, Kurtis D.;
- Mahale, Sakshi;
- Astling, David P.;
- Aisner, Dara L.;
- Le, Anh T.;
- Hinz, Trista K.;
- Vaishnavi, Aria;
- Bunn Jr, Paul A.;
- Heasley, Lynn E.;
- Tan, Aik-Choon;
- Camidge, D. Ross;
- Varella-Garcia, Marileila;
- Doebele, Robert C.
Publication type:
Article
Heterotrimeric G-Protein, Gα16, Is a Critical Downstream Effector of Non-Canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076895
By:
- Avasarala, Sreedevi;
- Bikkavilli, Rama Kamesh;
- Van Scoyk, Michelle;
- Zhang, Wei;
- Lapite, Ajibike;
- Hostetter, Logan;
- Byers, Joshua T.;
- Heasley, Lynn E.;
- Sohn, Jang Won;
- Winn, Robert A.
Publication type:
Article
Rapidly Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in NSCLC Cell Lines through De-Repression of FGFR2 and FGFR3 Expression.
Published in:
PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0014117
By:
- Ware, Kathryn E.;
- Marshall, Marianne E.;
- Heasley, Lydia R.;
- Marek, Lindsay;
- Hinz, Trista K.;
- Hercule, Paula;
- Helfrich, Barbara A.;
- Doebele, Robert C.;
- Heasley, Lynn E.
Publication type:
Article
Jnk2 Effects on Tumor Development, Genetic Instability and Replicative Stress in an Oncogene-Driven Mouse Mammary Tumor Model.
Published in:
PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010443
By:
- Peila Chen;
- O'Neal, Jamye F.;
- Ebelt, Nancy D.;
- Cantrell, Michael A.;
- Mitra, Shreya;
- Nasrazadani, Azadeh;
- Vandenbroek, Tracy L.;
- Heasley, Lynn E.;
- van den Berg, Carla L.
Publication type:
Article
An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer.
Published in:
BMC Genomics, 2015, v. 16, p. 1, doi. 10.1186/1471-2164-16-S12-S2
By:
- Ryall, Karen A.;
- Jihye Kim;
- Klauck, Peter J.;
- Jimin Shin;
- Minjae Yoo;
- Ionkina, Anastasia;
- Pitts, Todd M.;
- Tentler, John J.;
- Diamond, Jennifer R.;
- Eckhardt, S. Gail;
- Heasley, Lynn E.;
- Jaewoo Kang;
- Aik Choon Tan
Publication type:
Article
Mechanisms of rapid cancer cell reprogramming initiated by targeted receptor tyrosine kinase inhibitors and inherent therapeutic vulnerabilities.
Published in:
Molecular Cancer, 2018, v. 17, p. 1, doi. 10.1186/s12943-018-0816-y
By:
- Kleczko, Emily K.;
- Heasley, Lynn E.
Publication type:
Article
γ-catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth.
Published in:
Oncogene, 2002, v. 21, n. 49, p. 7497, doi. 10.1038/sj.onc.1205963
By:
- Winn, Robert A.;
- Bremnes, Roy M.;
- Bemis, Lynne;
- Franklin, Wilbur A.;
- Miller, York E.;
- Cool, Carlyne;
- Heasley, Lynn E.
Publication type:
Article
Activating mutations in the NH.
Published in:
Journal of Cellular Biochemistry, 1991, v. 47, n. 4, p. 359, doi. 10.1002/jcb.240470410
By:
- Gupta, Sunil K.;
- Dhanasekaran, N.;
- Heasley, Lynn E.;
- Johnson, Gary L.
Publication type:
Article
Autocrine and paracrine signaling through neuropeptide receptors in human cancer.
Published in:
Oncogene, 2001, v. 20, n. 13, p. 1563, doi. 10.1038/sj.onc.1204183
By:
- Heasley, Lynn E
Publication type:
Article
Expression and role of the embryonic protein SOX2 in head and neck squamous cell carcinoma.
Published in:
Carcinogenesis, 2014, v. 35, n. 7, p. 1
By:
- Schröck, Andreas;
- Bode, Maike;
- Göke, Friederike Johanna Maria;
- Bareiss, Petra Marion;
- Schairer, Rebekka;
- Wang, Hui;
- Franzen, Alin;
- Kirsten, Robert;
- van Bremen, Tobias;
- Queisser, Angela;
- Kristiansen, Glen;
- Heasley, Lynn;
- Bootz, Friedrich;
- Lengerke, Claudia;
- Perner, Sven
Publication type:
Article
Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response.
Published in:
2021
By:
- Korpela, Sean P.;
- Hinz, Trista K.;
- Oweida, Ayman;
- Kim, Jihye;
- Calhoun, Jacob;
- Ferris, Robert;
- Nemenoff, Raphael A.;
- Karam, Sana D.;
- Clambey, Eric T.;
- Heasley, Lynn E.
Publication type:
journal article
MANAGING EDITOR HISTORY.
Published in:
CEE: Chemical Engineering Education, 2016, v. 50, n. 1, p. 50
By:
- HEASLEY, LYNN
Publication type:
Article
Fibroblast Growth Factor Receptor 1 as a Putative Therapy Target in Colorectal Cancer.
Published in:
Digestion, 2013, v. 88, n. 3, p. 172, doi. 10.1159/000355018
By:
- Göke, Friederike;
- Göke, antonia;
- von Mässenhausen, anne;
- Franzen, alina;
- Sharma, Rakesh;
- Kirsten, Robert;
- Böhm, Diana;
- Kristiansen, Glen;
- Stenzinger, albrecht;
- Wynes, Murry;
- Hirsch, Fred R.;
- Weichert, Wilko;
- Heasley, Lynn;
- Buettner, Reinhard;
- Perner, Sven
Publication type:
Article
Multiple signaling conduits regulate global differentiation‐specific gene expression in PC12 cells.
Published in:
Journal of Cellular Physiology, 2004, v. 201, n. 3, p. 459, doi. 10.1002/jcp.20087
By:
- Lindsay Marek;
- Valerie Levresse;
- Claudia Amura;
- Eve Zentrich;
- Vicki Van Putten;
- Raphael A. Nemenoff;
- Lynn E. Heasley
Publication type:
Article
Durable responses to alectinib in murine models of EML4-ALK lung cancer requires adaptive immunity.
Published in:
NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00355-2
By:
- Kleczko, Emily K.;
- Hinz, Trista K.;
- Nguyen, Teresa T.;
- Gurule, Natalia J.;
- Navarro, Andre;
- Le, Anh T.;
- Johnson, Amber M.;
- Kwak, Jeff;
- Polhac, Diana I.;
- Clambey, Eric T.;
- Weiser-Evans, Mary;
- Merrick, Daniel T.;
- Yang, Michael C.;
- Patil, Tejas;
- Schenk, Erin L.;
- Heasley, Lynn E.;
- Nemenoff, Raphael A.
Publication type:
Article
A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00181-4
By:
- Gurule, Natalia J.;
- McCoach, Caroline E.;
- Hinz, Trista K.;
- Merrick, Daniel T.;
- Van Bokhoven, Adriaan;
- Kim, Jihye;
- Patil, Tejas;
- Calhoun, Jacob;
- Nemenoff, Raphael A.;
- Tan, Aik Choon;
- Doebele, Robert C.;
- Heasley, Lynn E.
Publication type:
Article
Evaluation of FGFR3 as a Therapeutic Target in Head and Neck Squamous Cell Carcinoma.
Published in:
2016
By:
- von Mässenhausen, Anne;
- Deng, Mario;
- Billig, Hannah;
- Queisser, Angela;
- Vogel, Wenzel;
- Kristiansen, Glen;
- Schröck, Andreas;
- Bootz, Friedrich;
- Göke, Friederike;
- Franzen, Alina;
- Heasley, Lynn;
- Kirfel, Jutta;
- Brägelmann, Johannes;
- Perner, Sven
Publication type:
journal article
Evaluation of KRASG12C inhibitor responses in novel murine KRASG12C lung cancer cell line models.
Published in:
Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1094123
By:
- Sisler, Daniel J.;
- Hinz, Trista K.;
- Le, Anh T.;
- Kleczko, Emily K.;
- Nemenoff, Raphael A.;
- Heasley, Lynn E.
Publication type:
Article
Upregulation of complement proteins in lung cancer cells mediates tumor progression.
Published in:
Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2022.1045690
By:
- Kleczko, Emily K.;
- Poczobutt, Joanna M.;
- Navarro, Andre C.;
- Laskowski, Jennifer;
- Johnson, Amber M.;
- Korpela, Sean P.;
- Gurule, Natalia J.;
- Heasley, Lynn E.;
- Hopp, Katharina;
- Weiser-Evans, Mary C. M.;
- Gottlin, Elizabeth B.;
- Bushey, Ryan T.;
- Campa, Michael J.;
- Patz Jr., Edward F.;
- Thurman, Joshua M.;
- Nemenoff, Raphael A.
Publication type:
Article
Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data.
Published in:
Bioinformatics, 2015, v. 31, n. 23, p. 3799, doi. 10.1093/bioinformatics/btv427
By:
- Ryall, Karen A.;
- Jimin Shin;
- Minjae Yoo;
- Hinz, Trista K.;
- Jihye Kim;
- Jaewoo Kang;
- Heasley, Lynn E.;
- Aik Choon Tan
Publication type:
Article
Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy.
Published in:
Bioinformatics, 2014, v. 30, n. 17, p. 2393, doi. 10.1093/bioinformatics/btu323
By:
- Kim, Jihye;
- Vasu, Vihas T.;
- Mishra, Rangnath;
- Singleton, Katherine R.;
- Yoo, Minjae;
- Leach, Sonia M.;
- Farias-Hesson, Eveline;
- Mason, Robert J.;
- Kang, Jaewoo;
- Ramamoorthy, Preveen;
- Kern, Jeffrey A.;
- Heasley, Lynn E.;
- Finigan, James H.;
- Tan, Aik Choon
Publication type:
Article
STAT3 Modulation of Regulatory T Cells in Response to Radiation Therapy in Head and Neck Cancer.
Published in:
2019
By:
- Oweida, Ayman J;
- Darragh, Laurel;
- Phan, Andy;
- Binder, David;
- Bhatia, Shilpa;
- Mueller, Adam;
- Court, Benjamin Van;
- Milner, Dallin;
- Raben, David;
- Woessner, Richard;
- Heasley, Lynn;
- Nemenoff, Raphael;
- Clambey, Eric;
- Karam, Sana D
Publication type:
journal article

Found: 28

EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.

Signalling in stem cells.

Concise Review: Regulation of Embryonic Stem Cell Lineage Commitment by Mitogen-Activated Protein Kinases.

Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib.

A miRNA Panel Predicts Sensitivity of FGFR Inhibitor in Lung Cancer Cell Lines.

An Inducible TGF-β2-TGFβR Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases.

Resistance to ROS1 Inhibition Mediated by EGFR Pathway Activation in Non-Small Cell Lung Cancer.

Heterotrimeric G-Protein, G<sub>α16</sub>, Is a Critical Downstream Effector of Non-Canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer.

Rapidly Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in NSCLC Cell Lines through De-Repression of FGFR2 and FGFR3 Expression.

Jnk2 Effects on Tumor Development, Genetic Instability and Replicative Stress in an Oncogene-Driven Mouse Mammary Tumor Model.

An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer.

Mechanisms of rapid cancer cell reprogramming initiated by targeted receptor tyrosine kinase inhibitors and inherent therapeutic vulnerabilities.

γ-catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth.

Activating mutations in the NH.

Autocrine and paracrine signaling through neuropeptide receptors in human cancer.

Expression and role of the embryonic protein SOX2 in head and neck squamous cell carcinoma.

Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response.

MANAGING EDITOR HISTORY.

Fibroblast Growth Factor Receptor 1 as a Putative Therapy Target in Colorectal Cancer.

Multiple signaling conduits regulate global differentiation‐specific gene expression in PC12 cells.

Durable responses to alectinib in murine models of EML4-ALK lung cancer requires adaptive immunity.

A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer.

Evaluation of FGFR3 as a Therapeutic Target in Head and Neck Squamous Cell Carcinoma.

Evaluation of KRAS<sup>G12C</sup> inhibitor responses in novel murine KRAS<sup>G12C</sup> lung cancer cell line models.

Upregulation of complement proteins in lung cancer cells mediates tumor progression.

Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data.

Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy.

STAT3 Modulation of Regulatory T Cells in Response to Radiation Therapy in Head and Neck Cancer.