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- Title
Tuberculosis prevention in HIV-infected pregnant women in South Africa.
- Authors
Martin, C. E.; Black, V.
- Abstract
The high burden of HIV and tuberculosis (TB) among pregnant women in South Africa contributes to a high maternal mortality rate. Isoniazid preventive therapy (IPT) is recommended for the prevention of active TB in HIV-infected individuals, including pregnant women. However, there are few data regarding IPT use in the latter, with concern regarding the concurrent use of IPT with nevirapine in pregnancy, as both treatments are hepatotoxic. The benefit and safety of IPT in HIV-infected pregnant women has not been established. We recommend a simplification of HIV and TB interventions by providing triple antiretroviral therapy to all HIV-infected pregnant women.
- Subjects
PREGNANT women; HIV infections; VIRUS diseases; TUBERCULOSIS; ANTIRETROVIRAL agents
- Publication
Southern African Journal of HIV Medicine, 2012, Vol 13, Issue 4, p182
- ISSN
1608-9693
- Publication type
Article
- DOI
10.4102/sajhivmed.v13i4.113