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- Title
HIPERPLASIA DO TIMO EM DOENTE COM SÍNDROME ANTIFOSFOLIPÍDICO.
- Authors
Carragoso, Adelino; Faria, Bernardo; Silva, José Roberto; Capelo, Joana; Vidinha, Joana; Santos, Carla Ferreira; Gaspar, Orlando
- Abstract
Thymus is an important central lymphoid organ that plays a pivotal role in the generation of peripheral T-lymphocytes. Thymoma and thymus hyperplasia have been associated with various autoimmune disorders, mainly myasthenia gravis. There is no established relationship between thymus pathology and antiphospholipid syndrome; however, there are some reported cases of antiphospholipid syndrome associated with myasthenia gravis or following thymectomy. We present the case of a patient with antiphospholipid syndrome and thymic lymphoid follicular hyperplasia. We discuss the association between both entities and suggest a diagnostic approach of a patient with a radiological disorder of the thymus and antiphospholipid syndrome.
- Subjects
HYPERPLASIA; CELLULAR pathology; AUTOIMMUNE diseases; THYMUS; T cells; MYASTHENIA gravis; ANTIPHOSPHOLIPID syndrome; THYMECTOMY; PATIENTS
- Publication
Acta Reumatológica Portuguesa, 2009, Vol 34, Issue 2, p251
- ISSN
0303-464X
- Publication type
Article