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- Title
Neural Stem Cells Harvested from Live Brains by Antibody-Conjugated Magnetic Nanoparticles.
- Authors
Lui, C. N. P.; Tsui, Y. P.; Ho, A. S. L.; Shum, D. K. Y.; Chan, Y. S.; Wu, C. T.; Li, H. W.; Tsang, S. C. Edman; Yung, K. K. L.
- Abstract
It stems from the magnetism: The extraction of stem/progenitor cells from the brain of live animals is possible using antibodies conjugated to magnetic nanoparticles (Ab‐MNPs). The Ab‐MNPs are introduced to a rat's brain with a superfine micro‐syringe. The stem cells attach to the Ab‐MNPs and are magnetically isolated and removed. They can develop into neurospheres and differentiate into different types of cells outside the subject body. The rat remains alive and healthy.
- Subjects
MAGNETIC nanoparticles; CELL analysis; IMMUNOGLOBULINS; LABORATORY rats; BRAIN anatomy
- Publication
Angewandte Chemie International Edition, 2013, Vol 52, Issue 47, p12298
- ISSN
1433-7851
- Publication type
Article
- DOI
10.1002/anie.201305482