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- Title
A Pilot Study on the Efficacy of a Treatment Algorithm to Detoxify Dental Implant Surfaces Affected by Peri-implantitis.
- Authors
Rosen, Paul S.; Qari, Maha; Froum, Stuart J.; Dibart, Serge; Chou, L. Lee
- Abstract
This in vitro pilot study was performed to determine whether a treatment algorithm including mechanical debridement, followed by air powder abrasion with glycine, followed by citric acid conditioning with vigorous flushing of the surface with sterile water after each step, is capable of decontaminating an infected implant surface. A total of 14 dental implants that were deemed hopeless due to advanced peri-implantitis were extracted. Of these, 6 implants served as tests and had their exposed surfaces treated with the decontamination protocol, 6 served as untreated controls, and 2 were mechanically treated only, followed by rubbing the surface with sterile saline. All implants were placed in culture with human osteoprogenitor cells for 72 hours, and evaluation was performed using scanning electron microscopy. The 6 test implants all demonstrated attachment and proliferation of the normal human osteoprogenitor cells on their prior exposed and decontaminated surfaces. All of the untreated control and the mechanically debrided, sterile water--treated implants failed to demonstrate this same success. The results suggest that this protocol can decontaminate an implant surface affected by peri-implantitis. Further studies are warranted to determine if this technique would demonstrate similar success over a greater number of implants and whether this outcome may occur in humans.
- Subjects
TREATMENT effectiveness; DENTAL implants; PERI-implantitis; DETOXIFICATION (Alternative medicine); OPERATIVE dentistry; MATHEMATICAL models; CELL proliferation; ALGORITHMS; CELL culture; CITRATES; DEBRIDEMENT; DECONTAMINATION (From gases, chemicals, etc.); GLYCINE; SCANNING electron microscopy; STEM cells; STERILIZATION (Disinfection); WATER; PILOT projects; IN vitro studies; THERAPEUTICS
- Publication
International Journal of Periodontics & Restorative Dentistry, 2018, Vol 38, Issue 2, p261
- ISSN
0198-7569
- Publication type
Article
- DOI
10.11607/prd.3203