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- Title
Successful Spouse Pregnancy of Male Patients with Severe Apalstic Anemia and Chronic Myelogenous Leukemia Using Spermatozoa Banked Prior to Bone Marrow Transplantation and Using the ICSI Procedure: Case Reports.
- Authors
Sung-Won Cho; Sook-Hwan Lee; Mik-Kyung Chung; Hyun-Ah Kim; Hyung-Min Chung; Yun-Jung lEe; Hwang Kwon; Tae-Ki Yoon; Kwang-Yul Cha
- Abstract
Purpose: To report two cases of successful spouse pregnancies which were conceived with longterm cryopreserved spermatozoa that had been collected prior to the male patients receiving a bone marrow transplant. Methods: The first case is the pregnant wife of a 25-year-old man with chronic myelogenous leukemia, whose semen was collected before bone marrow transplant and then cryopreserved, thawed, and then injected into the wife's eggs via ICSI. The second case is a 28-year-old man with severe aplastic anemia who became a father after his wife's eggs were fertilized via ICSI with thawed spermatozoa. Results: These two cases were achieved pregnancies. Conclusions: These cases support research that men with malignancy have the chance of fathering their own genetic children. Therefore, it is important to increase the awareness of clinicians, oncologists, and patients to the new developments in preserving fertility for cancer patients.
- Subjects
SPOUSES' legal relationship; PREGNANCY; FROZEN semen; TRANSPLANTATION of organs, tissues, etc.; APLASTIC anemia; MYELOID leukemia; CRYOPRESERVATION of organs, tissues, etc.
- Publication
Journal of Assisted Reproduction & Genetics, 2004, Vol 21, Issue 2, p59
- ISSN
1058-0468
- Publication type
Article
- DOI
10.1023/B:JARG.0000025940.98249.85