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- Title
Glycogen Synthase Kinase-3β Inhibition of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica Matsum).
- Authors
Yoshida, Jun; Nomura, Satomi; Nishizawa, Naoyuki; Ito, Yoshiaki; Kimura, Ken-Ichi
- Abstract
The article presents a study concerning Wasabi in relation to glycogen synthase kinase-3ß inhibition of 6-(methylsulfinyl)hexyl isothiocyanate. It mentions that isothiocyanate has shown adenosine triphosphate (ATP) competitive inhibition. It notes that the structure relationship has shown inhibitory possibility of methylsulfinyl isothiocyanate which is dependent of alkyl chain length and the sulfoxide.
- Subjects
WASABI; GLYCOGEN synthase kinase-3; SULFOXIDES; ADENOSINE triphosphate; ALKYLATION
- Publication
Bioscience, Biotechnology & Biochemistry, 2011, Vol 75, Issue 1, p136
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1271/bbb.100507