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- Title
19S- und 7S-Gedächtnis der Maus nach Erstimmunisierung mit einer immunogenen Schwellendosis von Schaferythrocyten.
- Authors
Finger, H.; Emmerling, P.; Offenhammer, A.
- Abstract
The primary immunization of mice with an immunogenic threshold dose of 5×10 sheep erythrocytes, at the cellular and humoral level, induces just a measurable immune response. Thereby only 0,8% of those 19S and 7S hemolysin-producing spleen cells were demonstrable, respectively, which were found after the primary immunization with a saturated immunogenic dose of 4×10 sheep erythrocytes. Nevertheless, secondary immunizations either with 5×10 or 4×10 sheep erythrocytes elicited typical secondary responses, characterized by the increased and accelerated formation of 7S producers. The findings presented allow the following conclusions:
- Publication
Medical Microbiology & Immunology, 1970, Vol 155, Issue 3, p203
- ISSN
0300-8584
- Publication type
Article
- DOI
10.1007/BF02275107