We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Neutrophils in viral infection.
- Authors
Naumenko, Victor; Turk, Madison; Jenne, Craig N.; Kim, Seok-Joo
- Abstract
Neutrophils are the first wave of recruited immune cells to sites of injury or infection and are crucial players in controlling bacterial and fungal infections. Although the role of neutrophils during bacterial or fungal infections is well understood, their impact on antiviral immunity is much less studied. Furthermore, neutrophil function in tumor pathogenesis and cancer treatment has recently received much attention, particularly within the context of oncolytic virus infection where neutrophils produce antitumor cytokines and enhance oncolysis. In this review, multiple functions of neutrophils in viral infections and immunity are discussed. Understanding the role of neutrophils during viral infection may provide insight into the pathogenesis of virus infections and the outcome of virus-based therapies.
- Subjects
NEUTROPHILS; ANTIVIRAL agents; VIRUS diseases; IMMUNOLOGY; BACTERIAL diseases; MYCOSES
- Publication
Cell & Tissue Research, 2018, Vol 371, Issue 3, p505
- ISSN
0302-766X
- Publication type
Article
- DOI
10.1007/s00441-017-2763-0