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- Title
Chemical composition and acetylcholinesterase inhibitory activity of Chassalia curviflora (Wall.) Thwaites essential oil.
- Authors
Nuzul Hakimi Wan SALLEH, Wan Mohd; NAFIAH, Mohd Azlan; KHAMIS, Shamsul
- Abstract
Chemical composition and acetylcholinesterase activity of the essential oil of Chassalia curviflora (Wall.) Thwaites (Rubiaceae) was examined for the first time. The essential oil was obtained by hydrodistillation and fully characterised by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of twenty-seven components were identified in the essential oil, which made up 91.2% of the total oil. The essential oil is composed mainly of caryophyllene oxide (22.4%), β-caryophyllene (16.5%), germacrene D (11.8%), (E)-nerolidol (9.2%), and elemol (5.5%). The essential oil showed significant activity against acetylcholinesterase with a percentage inhibition of 70.5%.
- Subjects
ACETYLCHOLINESTERASE inhibitors; RUBIACEAE; ESSENTIAL oils; FOOD composition; GAS chromatography
- Publication
Rivista Italiana delle Sostanze Grasse, 2021, Vol 98, Issue 2, p139
- ISSN
0035-6808
- Publication type
Article