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- Title
经支气管镜肺泡灌洗治疗重症 CAP 患者的疗效及安全性.
- Authors
杨添文; 曾小艺; 刘姝; 黄倩; 李梅华
- Abstract
Objective To study the efficacy and safety of bronchoalveolar lavage in the treatment of patients with severe CAP.Methods 76 patients with severe CAP were selected fromAugust,2016 to November,2018 in Ganmei Hospital Affiliated to Kunming Medical University(The First People's Hospital of Kunming) .All patients were randomly divided into 2 groups:treatment group (n = 38) and control group (n = 38) .The treatment group was treated with bronchoscopy and alveolar lavage. After 7 days, body temperature fluctuation, white blood cell, blood gas analysis (PaO2 and PaCO2) and total hospitalization time were observed.At the same time,we observedwhether there were serious adverse events during hospitalization in the two groups.Results After treatment, body temperature[treatment group(37.082±0.7822)℃,control group (37.603±0.7779) ℃], white blood cell[treatment group (9.058±1.8232) ×109,control group (11.41±.0599) ×109] and PaCO2[treatment group (42.84±6.092) mmHg,control group (48.63±6.162) mmHg] were decreased in the two groups,and the difference was statistically significant(P<0.05) .At the same time, the effect of bronchofiberscope lavage in the treatment group was more significant, and the decrease was more obvious, the difference was statistically significant (P<0.05) .After treatment, PaO2 [treatment group(82.12±8.867) mmHg,control group (67.87± 9.154) mmHg ]increased, and the difference was statistically significant compared with that before treatment( < 0.05) .At the same time, the curative effect of bronchoscopy lavage in the treatment group was better and the increase was more significant than the control group,the difference was statistically significant(P<0.05) .Hospitalization time [treatment group (13.97±3.537) d,control group (20.19±3.763) d]of patients in the treatment group was shorter than that in the control gorup, the difference was statistically significant(P<0.05) .Conclusion Bronchoscope alveolar lavage has significant clinical effect and no serious adverse reactions in the treatment of patients with severe CAP.
- Publication
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2019, Vol 40, Issue 12, p92
- ISSN
2095-610X
- Publication type
Article