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- Title
The predictive validity of health-related quality of life measures: mortality in a longitudinal population-based study.
- Authors
Kaplan, Mark S.; Berthelot, Jean-Marie; Feeny, David; McFarland, Bentson H.; Khan, Saeeda; Orpana, Heather
- Abstract
<bold>Objective: </bold>This study examined the association between health-related quality of life (HRQL) and mortality risk, and compared the predictive ability of Health Utilities Index Mark 3 (HUI3) with self-rated health (SRH).<bold>Methods: </bold>Data were from the 1994/95 Canadian National Population Health Survey, consisting of 12,375 women and men aged 18 and older. Cox proportional hazards regression models were performed to estimate mortality risk over eight years.<bold>Results: </bold>Mortality risks for people reporting good, fair, and poor health at baseline were, respectively, 1.44 (95% confidence interval [CI] 1.04, 2.00), 1.97 (1.35, 2.88), and 3.21 (2.08, 4.95) times greater than those who reported excellent health. In a model excluding SRH, the effect of HUI3 on mortality was strong and significant (HR = 0.47; 95%, 0.33, 0.67) when adjusted for possible confounders. When HUI3 and SRH were considered simultaneously, the effect of the HUI3 on mortality was somewhat attenuated, but still significant (HR = 0.61, 0.42, 0.89) after adjusting for potential confounders.<bold>Conclusions: </bold>Although SRH is a modestly stronger predictor of mortality than HUI3, HUI3 adds to the mortality prediction ability of SRH.
- Subjects
CANADA; QUALITY of life; MORTALITY; HEALTH surveys; REGRESSION analysis; MULTIVARIATE analysis
- Publication
Quality of Life Research, 2007, Vol 16, Issue 9, p1539
- ISSN
0962-9343
- Publication type
journal article
- DOI
10.1007/s11136-007-9256-7