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Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.20732
By:
- Kuchuan Chen;
- Tammy Szu-Yu Ho;
- Guang Lin;
- Kai Li Tan;
- Rasband, Matthew N.;
- Bellen, Hugo J.
Publication type:
Article
Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.16043
By:
- Kuchuan Chen;
- Guang Lin;
- Haelterman, Nele A.;
- Tammy Szu-Yu Ho;
- Tongchao Li;
- Zhihong Li;
- Duraine, Lita;
- Graham, Brett H.;
- Jaiswal, Manish;
- Shinya Yamamoto;
- Rasband, Matthew N.;
- Bellen, Hugo J.
Publication type:
Article
A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila.
Published in:
eLife, 2015, p. 1, doi. 10.7554/eLife.05338
By:
- Nagarkar-Jaiswal, Sonal;
- Pei-Tseng Lee;
- Campbell, Megan E.;
- Anguiano-Zarate, Stephanie;
- Gutierrez, Manuel Cantu;
- Busby, Theodore;
- Wen-Wen Lin;
- Bellen, Hugo J.;
- Kuchuan Chen;
- Yuchun He;
- Schulze, Karen L.;
- Booth, Benjamin W.;
- Evans-Holm, Martha;
- Hoskins, Roger A.;
- Venken, Koen J. T.;
- Levis, Robert W.;
- Spradling, Allan C.
Publication type:
Article
Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons.
Published in:
Cellular & Molecular Life Sciences, 2024, v. 81, n. 1, p. 1, doi. 10.1007/s00018-024-05340-x
By:
- Petrova, Veselina;
- Snavely, Andrew R.;
- Splaine, Jennifer;
- Zhen, Shannon;
- Singh, Bhagat;
- Pandey, Roshan;
- Chen, Kuchuan;
- Cheng, Anya;
- Hermawan, Crystal;
- Barrett, Lee B.;
- Smith, Jennifer A.;
- Woolf, Clifford J.
Publication type:
Article
Downregulation of the silent potassium channel Kv8.1 increases motor neuron vulnerability in amyotrophic lateral sclerosis.
Published in:
Brain Communications, 2024, v. 6, n. 3, p. 1, doi. 10.1093/braincomms/fcae202
By:
- Huang, Xuan;
- Lee, Seungkyu;
- Chen, Kuchuan;
- Kawaguchi, Riki;
- Wiskow, Ole;
- Ghosh, Sulagna;
- Frost, Devlin;
- Perrault, Laura;
- Pandey, Roshan;
- Klim, Joseph R;
- Boivin, Bruno;
- Hermawan, Crystal;
- Livak, Kenneth J;
- Geschwind, Daniel H;
- Wainger, Brian J;
- Eggan, Kevin C;
- Bean, Bruce P;
- Woolf, Clifford J
Publication type:
Article
<i>Drosophila</i> Tempura, a Novel Protein Prenyltransferase α Subunit, Regulates Notch Signaling Via Rab1 and Rab11.
Published in:
PLoS Biology, 2014, v. 12, n. 1, p. 1, doi. 10.1371/journal.pbio.1001777
By:
- Charng, Wu-Lin;
- Yamamoto, Shinya;
- Jaiswal, Manish;
- Bayat, Vafa;
- Xiong, Bo;
- Zhang, Ke;
- Sandoval, Hector;
- David, Gabriela;
- Gibbs, Stephen;
- Lu, Hsiang-Chih;
- Chen, Kuchuan;
- Giagtzoglou, Nikos;
- Bellen, Hugo J.
Publication type:
Article
Drosophila Neuroligin 2 is Required Presynaptically and Postsynaptically for Proper Synaptic Differentiation and Synaptic Transmission.
Published in:
Journal of Neuroscience, 2012, v. 32, n. 45, p. 16018, doi. 10.1523/JNEUROSCI.1685-12.2012
By:
- Yu-Chi Chen;
- Yong Qi Lin;
- Banerjee, Swati;
- Venken, Koen;
- Jingjun Li;
- Ismat, Afshan;
- Chen, Kuchuan;
- Duraine, Lita;
- Bellen, Hugo J.;
- Bhat, Manzoor A.
Publication type:
Article
Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.
Published in:
PLoS Genetics, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pgen.1006054
By:
- Li, Tongchao;
- Fan, Junkai;
- Blanco-Sánchez, Bernardo;
- Giagtzoglou, Nikolaos;
- Lin, Guang;
- Yamamoto, Shinya;
- Jaiswal, Manish;
- Chen, Kuchuan;
- Zhang, Jie;
- Wei, Wei;
- Lewis, Michael T.;
- Groves, Andrew K.;
- Westerfield, Monte;
- Jia, Jianhang;
- Bellen, Hugo J.
Publication type:
Article

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