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- Title
Potential Prebiotic and Anti-Obesity Effects of Codium fragile Extract.
- Authors
Oh, Suwon; Kim, Sungkeun; Jung, Kyoojin; Pham, Thi Ngoc Anh; Yang, Seunghwan; Ahn, Byungjae
- Abstract
Polysaccharides from marine algae exhibit beneficial biological activities. In this study, we examined the effect of Codium fragile extract (CFE) on prebiotic and anti-obesity activity through in vitro experiments. CFE increases the growth of specific beneficial microbial populations with concomitant decrease in pathogenic microbes. Further, total phenolic content (TPC), total flavonoid content (TFC), and DPPH radical scavenging activity (DPPH activity) after fermentation with CFE as the carbon source were higher than for glucose as the control. Moreover, CFE inhibited adipocyte differentiation by inducing differentiation-related factors when the induction of 3T3-L1 preadipocytes into adipocytes was induced. Therefore, we suggest that CFE can be used as a prebiotic material with an anti-obesity effect for human health.
- Subjects
MICROORGANISM populations; FLAVONOIDS; MARINE algae; EXTRACTS; POLYSACCHARIDES; FAT cells
- Publication
Applied Sciences (2076-3417), 2022, Vol 12, Issue 3, p959
- ISSN
2076-3417
- Publication type
Article
- DOI
10.3390/app12030959