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- Title
HYDROXYSTEROID DEHYDROGENASE ACTIVITY IN HUMAN SKIN II. FACTORS INFLUENCING HYDROXYSTEROID DEHYDROGENASE ACTIVITY IN SEBACEOUS GLANDS OF HUMAN SKIN.
- Authors
Muir, A. V.; Calman, K. C.; Thomson, J.; Macsween, M. P.; Milne, J. A.; Chakraborty, J.; Grant, J. K.
- Abstract
The effects of various factors on the histochemical demonstration of 3β-hydroxysteroid dehydrogenase activity in human skin were examined by a semiquantitative technique of granule counting. The optimum concentration of DHA was found to be 01 mg. ml. and of NAD 0-3 mg/ml. Vitamin K and nicotinamide enhanced the histochemical demonstration of the enzyme whereas cyproterone and cyproterone acetate inhibited the reaction.
- Subjects
DEHYDROGENASES; SKIN; VITAMIN K; NICOTINAMIDE; DOCOSAHEXAENOIC acid; AMIDES; CYPROTERONE acetate
- Publication
British Journal of Dermatology, 1968, Vol 80, Issue 10, p652
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/j.1365-2133.1968.tb11915.x