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- Title
Synthesis and antioxidant screening of Novel indole amines.
- Authors
Rubab, Syeda Laila; Nisar, Bushra; Raza, Abdul Rauf; Saadia, Mubshara; Tahir, Muhammad Nawaz; Sajjad, Noreen; Shajahan, Shanavas; Sharmila, V.; Acevedo, Roberto
- Abstract
Novel indoles amines have been synthesized and screened for antioxidant activity. Chiron approach is used to synthesis enantiopure heterocycles. Newly synthesized indole amines showed good antioxidant potential as compared to standard drugs. Novel indole amines (13–17) were synthesized and showed promising DPPH• scavenging activity, The H2O2 inhibition potential and the Ferric ion (Fe3+) reducing antioxidant power assay. The pharmacological activity is tested by targeting indolic diazepines derivatives.
- Subjects
AMINES; IRON ions; ANTIOXIDANTS; INDOLE compounds; DIAZEPINES
- Publication
Journal of the Iranian Chemical Society, 2022, Vol 19, Issue 7, p2693
- ISSN
1735-207X
- Publication type
Article
- DOI
10.1007/s13738-021-02482-8