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- Title
The effect of neck dissection on quality of life after chemoradiation
- Authors
Donatelli-Lassig, Amy Anne; Duffy, Sonia A.; Fowler, Karen E.; Ronis, David L.; Chepeha, Douglas B.; Terrell, Jeffrey E.
- Abstract
Objective: To determine differences in quality of life (QOL) between patients with head and neck cancer who receive chemoradiation versus chemoradiation and neck dissection. Methods: A prospective cohort study was conducted at two tertiary otolaryngology clinics and a Veterans Administration hospital. Sample: 103 oropharyngeal patients with Stage IV squamous cell carcinoma treated via chemoradiation ± neck dissection. Intervention: self-administered health survey to collect health, demographic, and QOL information pretreatment and 1 year later. Main outcome measures: QOL via SF-36 and HNQoL. Descriptive statistics were calculated for health/clinical characteristics, demographics, and QOL scores. t tests evaluated changes in QOL over time. Results: Sixty-five patients underwent chemoradiation and 38 patients underwent chemoradiation and neck dissection. Only the pain index of the SF-36 showed a significant difference between groups (P < 0.05) with the neck dissection group reporting greater pain. Conclusions: After post-treatment neck dissection, patients experience statistically significant decrement in bodily pain domain scores, but other QOL scores are similar to those of patients who underwent chemoradiation alone.
- Subjects
HEAD abnormalities; HEAD &; neck cancer; ACTIVITY programs in biology education; SURGERY
- Publication
Otolaryngology-Head & Neck Surgery, 2008, Vol 139, Issue 4, p511
- ISSN
0194-5998
- Publication type
Article
- DOI
10.1016/j.otohns.2008.07.007