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- Title
Ionic Liquid‐dependent Gold Nanoparticles of Purpurin‐18 for Cellular Imaging and Photodynamic Therapy In Vitro.
- Authors
Liu, Yang; Lee, Sang Hyeob; Lee, Woo Kyoung; Yoon, Il
- Abstract
In this study, we demonstrate IL-dependent PDT of GNPs using two water-soluble IL-type PSs to develop promising PSs with a suitable delivery system for PDT. The synthesis of IL-type PSs (PS1 and PS2) and GNPs (GNP1 and GNP2) was straightforward (Figures S1-S7, Supporting Information). The wt % of organic and inorganic contents in each GNP were used to calculate exact amount of each PS on corresponding GNP (GNP1 contains 492 nmol/mg PS1; GNP2 contains 573 nmol/mg PS2), and used in further cell study.[24] GNP1 had 11-fold higher photoactivity than GNP2 in which different result between GNP1 and GNP2 might be attributed by the faster drug delivery effect of GNP1 compared with GNP2 based on the corresponding each IL-type PS ability.
- Subjects
CELL imaging; GOLD nanoparticles; PHOTODYNAMIC therapy; NAD (Coenzyme); PHARMACOLOGY
- Publication
Bulletin of the Korean Chemical Society, 2020, Vol 41, Issue 2, p230
- ISSN
0253-2964
- Publication type
Article
- DOI
10.1002/bkcs.11943