We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Analysis of choroidal and central foveal thicknesses in acute anterior uveitis by enhanced-depth imaging optical coherence tomography.
- Authors
Mirinae Kim; Seung Yong Choi; Young-Hoon Park; Kim, Mirinae; Choi, Seung Yong; Park, Young-Hoon
- Abstract
<bold>Background: </bold>Currently, there are a limited number of reports of structural changes in the retina and choroid in acute anterior uveitis (AAU). The aim of this study was to evaluate choroidal and central foveal thicknesses during episodes of AAU.<bold>Methods: </bold>The medical records of 120 patients with AAU and 120 healthy subjects matched for age, sex, and spherical equivalent of refractive error were reviewed. Subjects were divided into group 1 (AAU-affected eyes), 2 (unaffected fellow eyes), and 3 (healthy control eyes).<bold>Results: </bold>In the uveitis group, etiologic diagnoses included human leukocyte antigen (HLA)-B27-associated (n = 71) and idiopathic (n = 49) AAU. The mean subfoveal choroidal thicknesses (SFCTs) in groups 1-3 were 326.7 ± 64.2, 296.1 ± 66.6, and 294.9 ± 41.7 μm, respectively. The corresponding mean central foveal thicknesses (CFTs) were 273.5 ± 29.3, 264.4 ± 24.6, and 263.0 ± 30.8 μm, respectively. The AAU group exhibited a significantly greater SFCT than the control groups (P < .001). Relative to the control group, while eyes with idiopathic AAU exhibited a significantly greater CFT, those with HLA-B27-associated AAU exhibited no such significant difference. Anterior chamber cell grade was not associated with SFCT or CFT.<bold>Conclusions: </bold>The SFCT increased significantly during AAU. This indicates the importance of OCT examination for detection of subclinical choroidal and retinal changes in all types of AAU.
- Subjects
IRIDOCYCLITIS; RESEARCH funding; RETINA; UVEA; OPTICAL coherence tomography; RETROSPECTIVE studies; CASE-control method; ACUTE diseases
- Publication
BMC Ophthalmology, 2017, Vol 17, p1
- ISSN
1471-2415
- Publication type
journal article
- DOI
10.1186/s12886-017-0628-7