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- Title
Donor Size Doesn’t Impact En Bloc Kidney Transplant Outcomes: A Single-Center Experience and Review of Literature.
- Authors
Spaggiari, Mario; Petrochenkov, Egor; Patel, Hiteshi; Di Cocco, Pierpaolo; Almario-Alvarez, Jorge; Fratti, Alberto; Tzvetanov, Ivo; Benedetti, Enrico
- Abstract
Few transplant programs use kidneys from donors with body weight (BW)<10 kg due to higher incidence of vascular and urological complications, and DGF. The purpose of this study was to investigate the non-inferiority of pediatric en bloc kidneys from donors with BW<10 kg. We performed a single-center retrospective analysis of en bloc kidney transplants from pediatric donor cohort (n = 46) from 2003 to 2021 and stratified the outcomes by donor BW (small group, donor BW<10 kg, n = 30; standard group, donor BW<10 kg, n = 16). Graft function, rate of early post-transplant complications, graft and patient survival were analyzed. Complication rates were similar between both groups with 1 case of arterial thrombosis in the smaller group. Overall graft and patient survival rates were similar between the small and the standard group (graft survival—90% vs. 100%, p = 0.09; patient survival—96.7 vs. 100%, p = 0.48). Serum creatinine at 1, 3, 5 years was no different between groups. Reoperation rate was higher in the small group (23.3% vs. 6.25%, p = 0.03). The allograft from small donors could be related to higher reoperation rate in the early post-transplant period, but not associated with lower long-term graft and patient survival.
- Subjects
HOMOGRAFTS; KIDNEY transplantation; TREATMENT effectiveness; LITERATURE reviews; OVERALL survival; GRAFT survival; BODY weight
- Publication
Transplant International, 2022, Vol 35, p1
- ISSN
0934-0874
- Publication type
Article
- DOI
10.3389/ti.2022.10731