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- Title
Expression of mucins on the mucosal surface of lungs of 4-week-old pigs.
- Authors
Chung Hyun Kim; Kichan Lee; Kiwon Han; Yeonsu Oh; Duyeol Kim; Hwi Won Seo; Changhoon Park; Mi-Kyoung Ha; Sung-Hoon Kim; Kyung-Dong Cho; Bog-Hieu Lee; Chanhee Chae
- Abstract
The aim of this study was to determine the immunoreactivity of normal small bronchial, bronchiolar, respiratory bronchiolar, and interalveolar epithelium using antibodies to six mucins: MUC1, MUC2, MUC4, MUC5AC, MUC5B, and MUC6. The large, gel-forming secreted mucins MUC2, MUC5AC, and MUC5B were widely expressed in the lower respiratory tract. The results of this study demonstrate that these secreted mucins form a gel to cover and protect the mucosal surface in the lower respiratory tract of pigs.
- Subjects
MUCINS; IMMUNE response; SWINE; COLLOIDS; LUNG physiology
- Publication
Veterinary Research Communications, 2011, Vol 35, Issue 4, p255
- ISSN
0165-7380
- Publication type
Article
- DOI
10.1007/s11259-011-9465-y