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- Title
Cluster Analysis of Chronic Rhinosinusitis Suggests Gender-Based Differences.
- Authors
Jurlin, Lana; Gregurić, Tomislav; Baudoin, Tomislav; Grgić, Marko Velimir; Pažanin, Leo; Košec, Andro; Scadding, Glenis; Kalogjera, Livije; Grgić, Marko Velimir
- Abstract
<bold>Purpose: </bold>We aimed to evaluate the interaction between the overall severity of chronic rhinosinusitis (CRS) before treatment and subjective improvement following surgical or medical treatment.<bold>Procedures: </bold>A group of 97 patients with CRS completed the visual analog scale (VAS) symptom score and the Sino-Nasal Outcome Test 22 (SNOT-22) questionnaire in the moment of their sinus computerized tomography (CT) scan. Data were analyzed via a 2-step cluster analysis based on gender, polyp presence, CT scan, and VAS scores for symptoms.<bold>Results: </bold>There were 3 clusters: the first cluster comprised 37 female patients with CRS without nasal polyps (CRSsNP), the second cluster comprised 30 patients with CRS and NP (CRSwNP; 15 males and 15 females); and third cluster had 30 male patients with CRS without NP (CRSsNP). Different symptom patterns between clusters were identified. After adjustment for polyp presence, gender, eosinophilia (p = 0.021), and the SNOT-22 score (p = 0.005) were found to be better outcome predictors than the CT score (p = 0.26).<bold>Conclusion: </bold>Long-term patient satisfaction is significantly associated with the subjective symptom severity prior to treatment, i.e., postnasal drip and overall disease severity (SNOT-22 score), but not with the objective severity of the disease (CT score and inflammation).
- Subjects
NASAL polyps; SINUSITIS; NASAL tumors; PATIENT satisfaction; VISUAL analog scale
- Publication
ORL, 2019, Vol 81, Issue 1, p1
- ISSN
0301-1569
- Publication type
journal article
- DOI
10.1159/000492966