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- Title
Diagnostic efficacy of endoscopic ultrasound-guided needle sampling for upper gastrointestinal subepithelial lesions: a meta-analysis.
- Authors
Zhang, Xiao-Cen; Li, Quan-Lin; Yu, Yong-Fu; Yao, Li-Qing; Xu, Mei-Dong; Zhang, Yi-Qun; Zhong, Yun-Shi; Chen, Wei-Feng; Zhou, Ping-Hong
- Abstract
<bold>Background: </bold>An increasing number of studies have been conducted on the use of endoscopic ultrasound (EUS)-guided needle sampling for upper gastrointestinal subepithelial lesions (SEL). However, reported diagnostic efficacy varies greatly.<bold>Objective: </bold>To summarize up current evidences on the diagnostic efficacy of EUS-guided needle sampling for upper GI SEL.<bold>Method: </bold>A reproducible strategy was used to search four databases. Search results were evaluated for eligibility, and the quality of eligible studies was assessed by QUADAS-2. Pooled efficacy of EUS-guided needle sampling in upper GI SEL was calculated. Procedure-related complications, diagnostic errors, and independent factors related to a higher success rate were also recorded and analyzed.<bold>Results: </bold>Seventeen studies, comprising 978 attempts of EUS-guided needle sampling, were included in a meta-analysis. Pooled diagnostic rate of EUS-guided needle sampling was 59.9 %, with a heterogeneity I (2) of 55.2 %. Subgroup analysis showed no difference in diagnostic rate among fine needle aspiration (FNA), trucut needle biopsy (TCB), and fine needle biopsy (FNB), or among 19-, 22-, and 25-G needles. Subgroup analysis and meta-regression suggested that the cell block method might be correlated with a higher diagnostic rate. Few severe complications were reported. Diagnosis errors were rare.<bold>Conclusion: </bold>EUS-guided needle sampling is a safe, but only moderately effective method for pathology diagnosis of upper GI SEL. Choice of FNA/TCB/FNB, or 19 G/22 G/25 G does not seem to alter the overall diagnostic rate.
- Subjects
ENDOSCOPIC surgery; OPERATIVE surgery; LAPAROSCOPIC surgery; SURGICAL equipment; GASTROINTESTINAL cancer; COLLECTION &; preservation of biological specimens; COMPARATIVE studies; ENDOSCOPIC ultrasonography; ESOPHAGEAL tumors; HYPODERMIC needles; RESEARCH methodology; MEDICAL cooperation; META-analysis; NEEDLE biopsy; RESEARCH; STOMACH tumors; SYSTEMATIC reviews; EVALUATION research; DIAGNOSIS
- Publication
Surgical Endoscopy & Other Interventional Techniques, 2016, Vol 30, Issue 6, p2431
- ISSN
1866-6817
- Publication type
journal article
- DOI
10.1007/s00464-015-4494-1