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- Title
In vitro activity of telithromycin, a new ketolide, against Chlamydia pneumoniae.
- Authors
Miyashita, Naoyuki; Fukano, Hiroshi; Niki, Yoshihito; Matsushima, Toshiharu; Miyashita, N; Fukano, H; Niki, Y; Matsushima, T
- Abstract
The in vitro activity of telithromycin, a new ketolide, was compared with those of roxithromycin, azithromycin, clarithromycin and erythromycin A against 20 strains of Chlamydia pneumoniae. The MICs and minimal chlamydiacidal concentrations of telithromycin for the 20 C. pneumoniae strains both ranged between 0.031 and 0.25 mg/L. Telithromycin was twice as active as roxithromycin, azithromycin and erythromycin A, but less active than clarithromycin. These results appear to indicate that telithromycin is an effective antibiotic that should play some role in the treatment of respiratory tract infections caused by C. pneumoniae.
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2001, Vol 48, Issue 3, p403
- ISSN
0305-7453
- Publication type
journal article
- DOI
10.1093/jac/48.3.403