We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Tentative interpretive criteria and quality control parameters for in-vitro susceptibility testing of Neisseria gonorrhoeae to two fluoroquinolones (PD 131628 and grepafloxacin (OPC 17116)).
- Authors
Sewell, David L.; Barry, Arthur L.; Allen, Stephen D.; Fuchs, Peter C.; Murray, Patrick R.; Tenover, Fred C.; Sewell, D L; Barry, A L; Allen, S D; Fuchs, P C; Murray, P R; Tenover, F C
- Abstract
The susceptibility of Neisseria gonorrhoeae to PD 131628 and grepafloxacin (OPC 17116) was evaluated by agar dilution and disc diffusion methods. A tentative susceptibility category for both fluoroquinolones included strains for which the MICs are ≤0.06mg/L and the zones of inhibition are ≥38mm for PD 131628 and ≥37 mm for grepafloxacin. Quality control studies with N. gonorrhoeae ATCC 49226 suggested that agar dilution MIC limits were 0.002–0.008 mg/L and 0.004–0.03 mg/L for PD 131628 and grepafloxacin, respectively. The zone size limits were 50–58 mm for PD 131628 and 44–52 mm for grepafloxacin.
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 1996, Vol 37, Issue 1, p139
- ISSN
0305-7453
- Publication type
journal article
- DOI
10.1093/jac/37.1.139