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- Title
An in vivo method for assessing the antimicrobial properties of topical antiseptics using artifically contaminated skin.
- Authors
Payne, D. N.; Eddowes, S.
- Abstract
A method is described for assessing the antimicrobial activity of topical antiseptics on human skin. The test, carried out on the forearms of volunteers, uses an inoculum of Stuphylococcus aureus. Up to four preparations may be tested at one time plus a placebo and untreated control site. The method has been used to compare four proprietary antiseptics and to evaluate their activity for up to one hour and has demonstrated a chloroxylenol, triclosan, EDTA combination product to be the most effective. The method is highly adaptable and may be used to evaluate activity versus other organisms and to examine other factors affecting antiseptic efficacy
- Publication
Letters in Applied Microbiology, 1990, Vol 10, Issue 2, p101
- ISSN
0266-8254
- Publication type
Article
- DOI
10.1111/j.1472-765X.1990.tb00275.x