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- Title
The aggressive behaviour of squamous cell carcinoma in epidermolysis bullosa: analysis of clinical outcomes and tumour characteristics in the Dutch EB Registry.
- Authors
Harrs, Clara; van den Akker, Peter C.; Baardman, Rosalie; Duipmans, José C.; Horváth, Barbara; van Kester, Marloes S.; Lemmink, Henny H.; Rácz, Emoke; Bolling, Marieke C.; Diercks, Gilles F.H.
- Abstract
Dear Editor, Epidermolysis bullosa (EB) is a group of rare heterogeneous genetic disorders characterized by mucocutaneous fragility with subsequent blisters and wounds.1 Depending on the level of blister formation, EB is classified into four main types: EB simplex (EBS), junctional EB (JEB), dystrophic EB (DEB) and Kindler EB (KEB). Here we present detailed data on the epidemiology, tumour characteristics and clinical outcomes of patients with EB-cSCCs collected over a 32-year period. Fifty-three tumours were primary cSCCs (68%), while the remaining tumours were locally recurrent cSCCs (16 of 78, 21%) or not specified (nine of 78, 12%).
- Subjects
EPIDERMOLYSIS bullosa; SQUAMOUS cell carcinoma; TUMORS; TREATMENT effectiveness
- Publication
British Journal of Dermatology, 2022, Vol 187, Issue 5, p824
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/bjd.21769