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- Title
Involvement of Insula and Cingulate Cortices in Control and Suppression of Natural Urges.
- Authors
Lerner, Alicja; Bagic, Anto; Hanakawa, Takashi; Boudreau, Eilis A.; Pagan, Fernando; Mari, Zoltan; Bara-Jimenez, William; Aksu, Murat; Sato, Susumu; Murphy, Dennis L.; Hallett, Mark
- Abstract
The physiology of control and suppression of natural urges is not well understood. We used [15O]H2O positron-emission tomography imaging to identify neural circuits involved in suppression of spontaneous blinking as a model of normal urges. Suppression of blinking was associated with prominent activation of bilateral insular-claustrum regions, right more than left; activation was also found in bilateral anterior cingulate cortex (ACC), supplementary motor areas, and the face area of the primary motor cortex bilaterally. These results suggest a central role for the insula possibly together with ACC in suppression of blinking.
- Publication
Cerebral Cortex, 2009, Vol 19, Issue 1, p218
- ISSN
1047-3211
- Publication type
Article
- DOI
10.1093/cercor/bhn074