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- Title
Neuroinvasive West Nile Virus Disease in an Elderly Patient with Diffuse Large B-Cell Lymphoma Treated with R-CHOP Therapy: A Case Report.
- Authors
Arslan, Barış; Gündüz, Hasan Murat; Ünlü, Nurdan; Çavuş, Gökhan; Menemenlioğlu, Dilek
- Abstract
Background: West Nile virus is an arthropod-borne virus (arbovirus) and emerging cause of significant illness in European and Mediterranean countries. West Nile virus infection can cause severe and potentially fatal neurological illnesses, including encephalitis, meningitis, and acute flaccid paralysis. Additionally, immunosuppression, alcohol abuse, old age, and diabetes mellitus are common factors associated with West Nile neuroinvasive disease. Case Report: In August 2018, a 60-year-old male patient with a history of diffuse large B-cell lymphoma initially presented with symptoms including abdominal pain and distention, nausea, and vomiting. Three days after open abdominal surgery due to adhesive small bowel obstruction, he developed fever, prominent tremors, and rapidly progressing flaccid paralysis. The identification of West Nile virus RNA in the serum sample led to the diagnosis of West Nile neuroinvasive disease. Conclusion: Clinicians should evaluate patients with acute flaccid paralysis for the evidence of West Nile neuroinvasive disease. It is particularly important for healthcare providers to consider West Nile neuroinvasive disease in the differential diagnosis of aseptic meningitis, encephalitis, and acute paralysis cases, especially in endemic areas.
- Subjects
WEST Nile fever diagnosis; ABDOMINAL pain; ANTINEOPLASTIC agents; B cell lymphoma; DIFFERENTIAL diagnosis; WEST Nile virus; ACUTE flaccid paralysis
- Publication
Balkan Medical Journal, 2019, Vol 36, Issue 5, p287
- ISSN
2146-3123
- Publication type
Article
- DOI
10.4274/balkanmedj.galenos.2019.2018.12.74