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- Title
Cerebral infarction and thrombotic meningoencephalitis in a calf due to candidiasis.
- Authors
Cruz Alves, Rodrigo; dos Santos Soares, Yanca Góes; de Lucena Carvalho, Fabrício Kleber; Ângelo Maia, Lisanka; Lombardo de Barros, Claudio Severo; Riet-Correa, Franklin; Medeiros Dantas, Antonio Flávio; Nogueira de Galiza, Glauco José
- Abstract
We described a case of cerebral infarction and thrombotic meningoencephalitis due to candidiasis in a seven-month-old calf. The death occurred three days after the onset of apathy, fever, and the head’s lateral deviation to the left. Macroscopic changes in the brain consisted of asymmetry of telencephalic hemispheres; the right hemisphere was enlarged, causing cerebellar herniation. A focally extensive red area was observed on the surface of the right occipital lobe. At cross-sections of the fixed brain, the lesions revealed to be extensive, redbrown, soft or cavitated areas affecting the white and grey matter from the level of the thalamus to the cerebellum and compressing subjacent structures. Histologically, there was acute, coalescent, multifocal necrosupurative meningoencephalitis, associated with vasculitis, congestion, thrombosis, edema, infarction, and intralesional fungal hyphae. The diagnosis of cerebral infarction and thrombotic meningoencephalitis due to candidiasis was made by the pathological changes, the staining and morphological characteristics of the agent, and immunohistochemistry. The cerebral infarction and thrombotic meningoencephalitis in cattle can result from vascular lesions due to infection by Candida sp.; although uncommon, this case demonstrated that candidiasis should be part of a list of differential diagnoses of severe brain injuries in cattle.
- Subjects
CEREBRAL infarction; MENINGOENCEPHALITIS; CANDIDIASIS; OCCIPITAL lobe; BRAIN injuries; PATHOLOGICAL physiology; CALVES; CEREBRAL dominance
- Publication
Ciência Rural, 2023, Vol 53, Issue 8, p1
- ISSN
0103-8478
- Publication type
Case Study
- DOI
10.1590/0103-8478cr20220254