We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE.
- Authors
de AVILA, Luciana Farias da Costa; TELMO, Paula de Lima; MARTINS, Lourdes Helena Rodrigues; GLAESER, Thais Aimeé; CONCEIÇÀO, Fabricio Rochedo; LEITE, Fabio Pereira Leivas; SCAINI, Carlos James
- Abstract
In a previous study our group found that the probiotic Saccharomyces boulardii was capable of reducing the intensity of infection in mice with toxocariasis. In order to assess whether the mechanism involved would be a direct action of the probiotic on Toxocara canis larvae, this study was designed. Both probiotics were singly cultivated in plates containing RPMI 1640 medium and T. canis larvae. S. boulardii and B. cereus var. toyoi cultures presented 97.6% and 95.7% of larvae with positive motility, respectively, and absence of color by the dye trypan blue, not representing significant difference to the control group (p > 0.05). We conclude that none of the probiotics showed in vitro effects on T. canis larvae and that the interaction with the intestinal mucosa is necessary for the development of the protective effect of S. boulardii.
- Subjects
SACCHAROMYCES; TOXOCARIASIS; PARASITOLOGY; MUCOUS membranes; GASTROINTESTINAL mucosa; ANIMAL nutrition; PROBIOTICS; DIAGNOSIS; THERAPEUTICS
- Publication
Revista do Instituto de Medicina Tropical de São Paulo, 2013, Vol 55, Issue 5, p363
- ISSN
0036-4665
- Publication type
Article
- DOI
10.1590/S0036-46652013000500012