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- Title
Effect of oral nutritional supplementation on the post-discharge nutritional status and quality of life of gastrointestinal cancer patients after surgery: a multi-center study.
- Authors
Ming-Wei Zhu; Xin Yang; Dian-Rong Xiu; Yong Yang; Guo-Xin Li; Wei-Guo Hu; Zhi-Gang Wang; Hong-Yuan Cui; Jun-Min Wei; Zhu, Ming-Wei; Yang, Xin; Xiu, Dian-Rong; Yang, Yong; Li, Guo-Xin; Hu, Wei-Guo; Wang, Zhi-Gang; Cui, Hong-Yuan; Wei, Jun-Min
- Abstract
<bold>Background and Objectives: </bold>To evaluate the effect of oral nutritional supplementation (ONS) on the postdischarge nutritional status and quality of life (QoL) of gastrointestinal cancer patients after surgery.<bold>Methods and Study Design: </bold>A multi-center study was conducted on gastrointestinal cancer patients who received surgical treatment from 2013-2015. All patients were screened using the Nutrition Risk Screening 2002 (NRS 2002) to assess nutritional risk. Patients with nutritional risk were randomized into two groups: patients in the study group (n=55) were given dietary guidance and ONS, control group (n=59) received only dietary guidance. Anthropometric measurements, nutrition-related laboratory tests, and gastrointestinal function scores were also collected and analyzed using Student's t test and analysis of variance (ANOVA). In addition, the EQ-5D was used to evaluate patients' QoL.<bold>Results: </bold>Compared with baseline measurements, the body weight of patients in the study group increased by 1.35±0.53 kg and 1.35±0.73 kg at 60 and 90 days, which were significantly higher than those in the control group (-1.01±0.54 kg, and -1.60±0.81 kg at 60 and 90 days). The results from ANOVA showed that only weight and BMI differed significantly between the study and control groups and also between different measurement times (p<0.01). No differences were found for the other indicators or QoL between the study groups.<bold>Conclusions: </bold>ONS may improve the weight and BMI of surgically treated gastrointestinal cancer patients postdischarge. However, these effects had little impact on patients' QoL.
- Subjects
GASTROINTESTINAL cancer; NUTRITIONAL status; CANCER patients; QUALITY of life; ANALYSIS of variance; STAPLERS (Surgery); FEEDING tubes
- Publication
Asia Pacific Journal of Clinical Nutrition, 2019, Vol 28, Issue 3, p450
- ISSN
0964-7058
- Publication type
journal article
- DOI
10.6133/apjcn.201909_28(3).0004