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- Title
Determinants and nutritional assessment value of hand grip strength in patients hospitalized with cancer.
- Authors
Chun-lei Hu; Miao Yu; Kai-tao Yuan; Hong-lan Yu; Ying-ying Shi; Jia-jun Yang; Wei Li; Hai-ping Jiang; Zeng-ning Li; Hong-xia Xu; Yi Ba; Kun-hua Wang; Su-yi Li; Han-ping Shi; Hu, Chun-Lei; Yu, Miao; Yuan, Kai-Tao; Yu, Hong-Lan; Shi, Ying-Ying; Yang, Jia-Jun
- Abstract
<bold>Background and Objectives: </bold>Hand grip strength (HGS) has emerged as a predictor of the nutritional status. However, many factors may modify the malnutrition-HGS association. This study explored the nutritional assessment value and determinants of HGS in patients hospitalized with cancer.<bold>Methods and Study Design: </bold>In this multicenter, retrospective, observational study (11,314 patients), the Receiver operator characteristic curve was used to observe HGS and nutritional status sensitivity/specificity. Sex; age; height; weight; mid-upper arm circumference (MAMC); Patient-Generated Subjective Global Assessment (PG-SGA) score; Karnofsky score; physical function (PF) domain; cognitive function (CF) domain; global health and quality of life (QL) domain of EORTC QLQ-C30 (a quality of life instrument designed by the European Organization for Research and Treatment of Cancer); and albumin, prealbumin, and hemoglobin levels were included in a Stepwise analysis model to identify the factors influencing HGS.<bold>Results: </bold>HGS showed a very low diagnostic value and accuracy for identifying severe malnourishment (area under the curve, 0.615-0.640; p<0.01). HGS positively correlated with sex; height; weight; MAMC; Karnofsky score; QL, PF, and CF domains; and hemoglobin and prealbumin levels (Beta= 0.02-0.42, p<=0.05), and negatively with age (Beta=-0.19, p<0.01). However, the PG-SGA score was excluded because of its very limited contribution to HGS variability.<bold>Conclusions: </bold>HGS is a mutifactorial index. The use of HGS cutoff values to identify malnutrition is markedly challenging. Thus, HGS may be of limited use as a predictor of nutritional status.
- Subjects
GRIP strength; HEMOGLOBINS; NUTRITIONAL status; HEALTH status indicators; TRANSTHYRETIN
- Publication
Asia Pacific Journal of Clinical Nutrition, 2018, Vol 27, Issue 4, p777
- ISSN
0964-7058
- Publication type
journal article
- DOI
10.6133/apjcn.072017.04