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- Title
Efficacy of digital cognitive behavioral therapy for moderate-to-severe symptoms of generalized anxiety disorder: A randomized controlled trial.
- Authors
Carl, Jenna R.; Miller, Christopher B.; Henry, Alasdair L.; Davis, Michelle L.; Stott, Richard; Smits, Jasper A. J.; Emsley, Richard; Gu, Jenny; Shin, Olivia; Otto, Michael W.; Craske, Michelle G.; Saunders, Kate E. A.; Goodwin, Guy M.; Espie, Colin A.
- Abstract
<bold>Background: </bold>Cognitive behavioral therapy (CBT) is an efficacious intervention for generalized anxiety disorder (GAD). Digital CBT may provide a scalable means of delivering CBT at a population level. We investigated the efficacy of a novel digital CBT program in those with GAD for outcomes of anxiety, worry, depressive symptoms, sleep difficulty, wellbeing, and participant-specific quality of life.<bold>Methods: </bold>This online, two-arm parallel-group superiority randomized controlled trial compared digital CBT with waitlist control in 256 participants with moderate-to-severe symptoms of GAD. Digital CBT (Daylight), was delivered using participants' own smartphones. Online assessments took place at baseline (Week 0; immediately preceding randomization), mid-intervention (Week 3; from randomization), post-intervention (Week 6; primary endpoint), and follow-up (Week 10).<bold>Results: </bold>Overall, 256 participants were randomized and intention-to-treat analysis found Daylight reduced symptoms of anxiety compared with waitlist control at post-intervention, reflecting a large effect size (adjusted difference [95% CI]: 3.22 [2.14, 4.31], d = 1.08). Significant improvements were found for measures of worry; depressive symptoms, sleep difficulty, wellbeing, and participant-specific quality of life.<bold>Conclusion: </bold>Digital CBT (Daylight) appears to be safe and efficacious for symptoms of anxiety, worry, and further measures of mental health compared with waitlist control in individuals with GAD.
- Subjects
GENERALIZED anxiety disorder; COGNITIVE therapy; SYMPTOMS; RANDOMIZED controlled trials; MENTAL depression; ANXIETY
- Publication
Depression & Anxiety (1091-4269), 2020, Vol 37, Issue 12, p1168
- ISSN
1091-4269
- Publication type
journal article
- DOI
10.1002/da.23079