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- Title
Low-molecular-weight heparin associated with reduced fetal fraction and subsequent false-negative cell-free DNA test result for trisomy 21.
- Authors
Lee, M.‐H.; Lee, M-H; Ma, G.‐C.; Ma, G-C; Chen, M.; Wu, W.‐J.; Wu, W-J; Lee, Mei-Hui; Ma, Gwo-Chin; Wu, Wan-Ju; Chen, Ming; Lin, Y.‐S.; Lin, Yi-Shing; Lin, Y-S
- Abstract
Cell-free DNA (cfDNA) screening for fetal trisomy 21, 18, and 13 is now widely used in clinical practice. However, false-positives and false-negatives did occur1,2 . Actually, the majority of fetal cfDNA in maternal blood is from placental trophoblasts.
- Subjects
HEPARIN; TRISOMY; DNA; ABORTION; HIGH-risk pregnancy; BODY mass index; TROPHOBLAST
- Publication
Ultrasound in Obstetrics & Gynecology, 2018, Vol 51, Issue 2, p276
- ISSN
0960-7692
- Publication type
letter
- DOI
10.1002/uog.17473