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- Title
Efficacy of ozonized sunflower oil in the treatment of tinea pedis.
- Authors
Menéndez, S.; Falcón, L.; Simón, D. R.; Landa, N.
- Abstract
Summary. Ozonized sunflower oil, Oleozon® , has a remarkable germicidal action. In the present study, the efficacy of Oleozon® in the treatment of tinea pedis was demonstrated in a controlled randomized phase III assay, comparing topical Oleozon® with ketoconazole cream 2% (Nizoral® ) in 200 patients (100 in each group). The treatment administered was twice per day for a period of 6 weeks. The efficacy was evaluated clinically (disappearance of all lesions, with or without negative mycological results) and mycologically (negative culture results). A complete clinical and mycological cure was obtained in 75 and 81% for Oleozon® and ketoconazole, respectively, with no significant differences between both groups. No side-effects or bacterial super-infections were observed. Patients were evaluated 6 months after the end of the treatment and no recurrence was observed in the Oleozon® group. Oleozon® can be an effective alternative low-cost antimycotic drug.
- Subjects
ATHLETE'S foot treatment; SUNFLOWER seed oil; ANTIFUNGAL agents; THERAPEUTICS
- Publication
Mycoses, 2002, Vol 45, Issue 7/8, p329
- ISSN
0933-7407
- Publication type
Article
- DOI
10.1046/j.1439-0507.2002.00780.x