We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19.
- Authors
Remppis, Jonathan; Ganzenmueller, Tina; Kohns Vasconcelos, Malte; Heinzel, Oliver; Handgretinger, Rupert; Renk, Hanna
- Abstract
<bold>Background: </bold>While our knowledge about COVID-19 in adults has rapidly increased, data on the course of disease and outcome in children with different comorbidities is still limited.<bold>Methods: </bold>Prospective, observational study at a tertiary care children's hospital in southern Germany. Clinical and virology data from all paediatric patients admitted with SARS-CoV-2 infection at our hospital were prospectively assessed.<bold>Results: </bold>Between March and November 2020, 14 patients were admitted with COVID-19. One patient was admitted a second time with COVID-19 6 months after initial disease. Among seven patients with severe underlying comorbidities, three developed multisystem inflammatory syndrome (MIS-C), two were admitted to the paediatric intensive care unit. One patient needed invasive ventilation. Another patient died shortly after discharge of COVID-19-related complications.<bold>Conclusions: </bold>While COVID-19 generally causes mild disease in children, severe respiratory illness and MIS-C occur, in some cases with fatal outcome. Children with underlying diseases might be at special risk for severe disease.
- Subjects
GERMANY; COVID-19; HOSPITAL care; PEDIATRIC intensive care; TERTIARY care; HOSPITAL care of children
- Publication
BMC Infectious Diseases, 2021, Vol 21, Issue 1, p1
- ISSN
1471-2334
- Publication type
journal article
- DOI
10.1186/s12879-021-05791-8