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- Title
Phase 2 Trial of Sorafenib in Patients With Advanced Urothelial Cancer.
- Authors
Dreicer, Robert; Li, Hailun; Stein, Mark; DiPaola, Robert; Eleff, Michael; Roth, Bruce J.; Wilding, George
- Abstract
The article presents a study which determines the activity as well as the toxicity of sorafenib in a multi-institutional setting in patients who were given the treatment with one prior chemotherapy regimen. Study shows no therapy-related deaths nor was an effective second-line systemic chemotherapy for patients. It is concluded that investigation of tyrosine kinase inhibitors is warranted through the use of different trial designs.
- Subjects
DRUG therapy; TOXICITY testing; PROTEIN-tyrosine kinases; AMINO acids; CANCER patients
- Publication
Cancer (0008543X), 2009, Vol 115, Issue 18, p4090
- ISSN
0008-543X
- Publication type
Article
- DOI
10.1002/cncr.24467