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Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09133-9
By:
- Bai, Xiyuan;
- Buckle, Ashley M.;
- Vladar, Eszter K.;
- Janoff, Edward N.;
- Khare, Reeti;
- Ordway, Diane;
- Beckham, David;
- Fornis, Lorelenn B.;
- Majluf-Cruz, Abraham;
- Fugit, Randolph V.;
- Freed, Brian M.;
- Kim, Soohyun;
- Sandhaus, Robert A.;
- Chan, Edward D.
Publication type:
Article
Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09133-9
By:
- Bai, Xiyuan;
- Buckle, Ashley M.;
- Vladar, Eszter K.;
- Janoff, Edward N.;
- Khare, Reeti;
- Ordway, Diane;
- Beckham, David;
- Fornis, Lorelenn B.;
- Majluf-Cruz, Abraham;
- Fugit, Randolph V.;
- Freed, Brian M.;
- Kim, Soohyun;
- Sandhaus, Robert A.;
- Chan, Edward D.
Publication type:
Article
Analysis of alpha‐1‐antitrypsin (AAT)‐regulated, glucocorticoid receptor‐dependent genes in macrophages reveals a novel host defense function of AAT.
Published in:
Physiological Reports, 2024, v. 12, n. 14, p. 1, doi. 10.14814/phy2.16124
By:
- Bai, Xiyuan;
- Gao, Junfeng;
- Guan, Xiaoyu;
- Narum, Drew E.;
- Fornis, Lorelenn B.;
- Griffith, David E.;
- Gao, Bifeng;
- Sandhaus, Robert A.;
- Huang, Hua;
- Chan, Edward D.
Publication type:
Article
IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease.
Published in:
International Immunology, 2011, v. 23, n. 11, p. 679, doi. 10.1093/intimm/dxr075
By:
- Bai, Xiyuan;
- Ovrutsky, Alida R.;
- Kartalija, Marinka;
- Chmura, Kathryn;
- Kamali, Amanda;
- Honda, Jennifer R.;
- Oberley-Deegan, Rebecca E.;
- Dinarello, Charles A.;
- Crapo, James D.;
- Chang, Ling-Yi;
- Chan, Edward D.
Publication type:
Article
Identification and characterization of a novel testis-specific gene CKT2, which encodes a substrate for protein kinase CK2.
Published in:
Nucleic Acids Research, 2009, v. 37, n. 8, p. 2699, doi. 10.1093/nar/gkp094
By:
- Bai, Xiyuan;
- Silvius, Derek;
- Chan, Edward D.;
- Escalier, Denise;
- Xu, Shaun Xin
Publication type:
Article
Pathogenic Nontuberculous Mycobacteria Resist and Inactivate Cathelicidin: Implication of a Novel Role for Polar Mycobacterial Lipids.
Published in:
PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0126994
By:
- Honda, Jennifer R.;
- Hess, Tamara;
- Malcolm, Kenneth C.;
- Ovrutsky, Alida R.;
- Bai, Xiyuan;
- Irani, Vida R.;
- Dobos, Karen M.;
- Chan, Edward D.;
- Flores, Sonia C.
Publication type:
Article
Inhibition of Nuclear Factor-Kappa B Activation Decreases Survival of <i>Mycobacterium tuberculosis</i> in Human Macrophages.
Published in:
PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061925
By:
- Bai, Xiyuan;
- Feldman, Nicole E.;
- Chmura, Kathryn;
- Ovrutsky, Alida R.;
- Su, Wen-Lin;
- Griffin, Laura;
- Pyeon, Dohun;
- McGibney, Mischa T.;
- Strand, Matthew J.;
- Numata, Mari;
- Murakami, Seiji;
- Gaido, Loretta;
- Honda, Jennifer R.;
- Kinney, William H.;
- Oberley-Deegan, Rebecca E.;
- Voelker, Dennis R.;
- Ordway, Diane J.;
- Chan, Edward D.
Publication type:
Article
The URA5 gene encoding orotate-phosphoribosyl transferase of the yeast Kluyveromyces lactis: Cloning, sequencing and use as a selectable marker.
Published in:
Yeast, 1999, v. 15, n. 13, p. 1393, doi. 10.1002/(SICI)1097-0061(19990930)15:13<1393::AID-YEA452>3.0.CO;2-F
By:
- Bai, Xiyuan;
- Larsen, Michael;
- Meinhardt, Friedhelm
Publication type:
Article
Cigarette Smoke Increases Susceptibility to Tuberculosis—Evidence From In Vivo and In Vitro Models.
Published in:
Journal of Infectious Diseases, 2011, v. 203, n. 9, p. 1240, doi. 10.1093/infdis/jir009
By:
- Shang, Shaobin;
- Ordway, Diane;
- Henao-Tamayo, Marcela;
- Bai, Xiyuan;
- Oberley-Deegan, Rebecca;
- Shanley, Crystal;
- Orme, Ian M.;
- Case, Stephanie;
- Minor, Maisha;
- Ackart, David;
- Hascall-Dove, Laurel;
- Ovrutsky, Alida R.;
- Kandasamy, Pitchaimani;
- Voelker, Dennis R.;
- Lambert, Cherie;
- Freed, Brian M.;
- Iseman, Michael D.;
- Basaraba, Randall J.;
- Chan, Edward D.
Publication type:
Article
Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01417
By:
- Bai, Xiyuan;
- Bai, An;
- Honda, Jennifer R.;
- Eichstaedt, Charles;
- Musheyev, Ariel;
- Feng, Zhihong;
- Huitt, Gwen;
- Harbeck, Ronald;
- Kosmider, Beata;
- Sandhaus, Robert A.;
- Chan, Edward D.
Publication type:
Article
Cigarette Smoke Increases Susceptibility to Tuberculosis—Evidence From In Vivo and In Vitro Models.
Published in:
Journal of Infectious Diseases, 1916, v. 19, n. 9, p. 1240
By:
- Shang, Shaobin;
- Ordway, Diane;
- Henao-Tamayo, Marcela;
- Bai, Xiyuan;
- Oberley-Deegan, Rebecca;
- Shanley, Crystal;
- Orme, Ian M.;
- Case, Stephanie;
- Minor, Maisha;
- Ackart, David;
- Hascall-Dove, Laurel;
- Ovrutsky, Alida R.;
- Kandasamy, Pitchaimani;
- Voelker, Dennis R.;
- Lambert, Cherie;
- Freed, Brian M.;
- Iseman, Michael D.;
- Basaraba, Randall J.;
- Chan, Edward D.
Publication type:
Article
Elucidating the Pathogenesis of Nontuberculous Mycobacterial Lung Disease: Lesson from the Six Blind Men and the Elephant.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2018, v. 58, n. 2, p. 142, doi. 10.1165/rcmb.2017-0317ed
By:
- Honda, Jennifer R.;
- Xiyuan Bai;
- Chan, Edward D.
Publication type:
Article
Nicotine Impairs Macrophage Control of Mycobacterium tuberculosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2017, v. 57, n. 3, p. 324, doi. 10.1165/rcmb.2016-0270OC
By:
- Xiyuan Bai;
- Stitzel, Jerry A.;
- Bai, An;
- Zambrano, Cristian A.;
- Phillips, Matthew;
- Marrack, Philippa;
- Chan, Edward D.
Publication type:
Article
Host Immune Response to Rapidly Growing Mycobacteria, an Emerging Cause of Chronic Lung Disease.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2010, v. 43, n. 4, p. 387, doi. 10.1165/rcmb.2009-0276TR
By:
- Chan, Edward D.;
- Xiyuan Bai;
- Kartalija, Marinka;
- Orme, Ian M.;
- Ordway, Diane J.
Publication type:
Article
Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis.
Published in:
Frontiers in Cellular & Infection Microbiology, 2023, p. 01, doi. 10.3389/fcimb.2023.1216492
By:
- Xiyuan Bai;
- Verma, Deepshikha;
- Garcia, Cindy;
- Musheyev, Ariel;
- Kim, Kevin;
- Fornis, Lorelenn;
- Griffith, David E.;
- Li Li;
- Whittel, Nicholas;
- Gadwa, Jacob;
- Ohanjanyan, Tamara;
- Eggleston, Matthew J.;
- Galvan, Manuel;
- Freed, Brian M.;
- Ordway, Diane;
- Chan, Edward D.
Publication type:
Article
Use of Digital Droplet PCR to Detect Mycobacterium tuberculosis DNA in Whole Blood-Derived DNA Samples from Patients with Pulmonary and Extrapulmonary Tuberculosis.
Published in:
Frontiers in Cellular & Infection Microbiology, 2017, v. 7, p. 1, doi. 10.3389/fcimb.2017.00369
By:
- Jiaru Yang;
- Xinlin Han;
- Aihua Liu;
- Xiyuan Bai;
- Cuiping Xu;
- Fukai Bao;
- Shi Feng;
- Lvyan Tao;
- Mingbiao Ma;
- Yun Peng
Publication type:
Article
Patients with Nontuberculous Mycobacterial Lung Disease Exhibit Unique Body and Immune Phenotypes.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2013, v. 187, n. 2, p. 197, doi. 10.1164/rccm.201206-1035oc
By:
- Kartalija, Marinka;
- Ovrutsky, Alida R.;
- Bryan, Courtney L.;
- Pott, Gregory B.;
- Fantuzzi, Giamila;
- Thomas, Jacob;
- Strand, Matthew J.;
- Xiyuan Bai;
- Ramamoorthy, Preveen;
- Rothman, Micol S.;
- Nagabhushanam, Vijaya;
- McDermott, Michael;
- Levin, Adrah R.;
- Frazer-Abel, Ashley;
- Giclas, Patricia C.;
- Korner, Judith;
- Iseman, Michael D.;
- Shapiro, Leland;
- Chan, Edward D.
Publication type:
Article
A Trojan Horse Strategy to Deliver Amikacin to Mycobacterial Granulornas.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2011, v. 184, n. 7, p. 860, doi. 10.1164/ajrccm.184.7.860
By:
- OVRUTSKY, ALIDA R.;
- KARTALIJA, MARINKA;
- BAI, XIYUAN;
- CHAN, EDWARD D.;
- MONTES-WORBOYS, ANA;
- Brown, Scott;
- ANTONY, VEENA B.
Publication type:
Article
A trojan horse strategy to deliver amikacin to mycobacterial granulomas.
Published in:
2011
By:
- Ovrutsky AR;
- Kartalija M;
- Bai X;
- Chan ED;
- Ovrutsky, Alida R;
- Kartalija, Marinka;
- Bai, Xiyuan;
- Chan, Edward D
Publication type:
Letter
Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence.
Published in:
Biochemical Society Transactions, 2023, v. 51, n. 3, p. 1361, doi. 10.1042/BST20230078
By:
- Xiyuan Bai;
- Schountz, Tony;
- Buckle, Ashley M.;
- Talbert, Janet L.;
- Sandhaus, Robert A.;
- Chan, Edward D.
Publication type:
Article
Curcumin enhances human macrophage control of Mycobacterium tuberculosis infection.
Published in:
Respirology, 2016, v. 21, n. 5, p. 951, doi. 10.1111/resp.12762
By:
- Bai, Xiyuan;
- Oberley‐Deegan, Rebecca E.;
- Bai, An;
- Ovrutsky, Alida R.;
- Kinney, William H.;
- Weaver, Michael;
- Zhang, Gong;
- Honda, Jennifer R.;
- Chan, Edward D.
Publication type:
Article
Epidemiologic link between tuberculosis and cigarette/biomass smoke exposure: Limitations despite the vast literature.
Published in:
Respirology, 2015, v. 20, n. 4, p. 556, doi. 10.1111/resp.12515
By:
- Bishwakarma, Raju;
- Kinney, William H.;
- Honda, Jennifer R.;
- Mya, Jenny;
- Strand, Matthew J.;
- Gangavelli, Avani;
- Bai, Xiyuan;
- Ordway, Diane J.;
- Iseman, Michael D.;
- Chan, Edward D.
Publication type:
Article
The Inhibition of Serine Proteases by Serpins Is Augmented by Negatively Charged Heparin: A Concise Review of Some Clinically Relevant Interactions.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1804, doi. 10.3390/ijms25031804
By:
- Chan, Edward D.;
- King, Paul T.;
- Bai, Xiyuan;
- Schoffstall, Allen M.;
- Sandhaus, Robert A.;
- Buckle, Ashley M.
Publication type:
Article
Differential Responses by Human Macrophages to Infection With Mycobacterium tuberculosis and Non-tuberculous Mycobacteria.
Published in:
Frontiers in Microbiology, 2020, p. 1, doi. 10.3389/fmicb.2020.00116
By:
- Feng, Zhihong;
- Bai, Xiyuan;
- Wang, Tao;
- Garcia, Cindy;
- Bai, An;
- Li, Li;
- Honda, Jennifer R.;
- Nie, Xiuhong;
- Chan, Edward D.
Publication type:
Article
Caspase-3-independent apoptotic pathways contribute to interleukin-32γ-mediated control of Mycobacterium tuberculosis infection in THP-1 cells.
Published in:
BMC Microbiology, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12866-015-0366-z
By:
- Xiyuan Bai;
- Kinney, William H.;
- Wen-Lin Su;
- Bai, An;
- Ovrutsky, Alida R.;
- Honda, Jennifer R.;
- Netea, Mihai G.;
- Henao-Tamayo, Marcela;
- Ordway, Diane J.;
- Dinarello, Charles A.;
- Chan, Edward D.
Publication type:
Article

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