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- Title
Induced pluripotent stem cells from highly endangered species.
- Authors
Friedrich Ben-Nun, Inbar; Montague, Susanne C; Houck, Marlys L; Tran, Ha T; Garitaonandia, Ibon; Leonardo, Trevor R; Wang, Yu-Chieh; Charter, Suellen J; Laurent, Louise C; Ryder, Oliver A; Loring, Jeanne F
- Abstract
For some highly endangered species there are too few reproductively capable animals to maintain adequate genetic diversity, and extraordinary measures are necessary to prevent extinction. We report generation of induced pluripotent stem cells (iPSCs) from two endangered species: a primate, the drill, Mandrillus leucophaeus and the nearly extinct northern white rhinoceros, Ceratotherium simum cottoni. iPSCs may eventually facilitate reintroduction of genetic material into breeding populations.
- Subjects
PLURIPOTENT stem cells; ENDANGERED species; WHITE rhinoceros; FIBROBLASTS; IMMUNOCYTOCHEMISTRY
- Publication
Nature Methods, 2011, Vol 8, Issue 10, p829
- ISSN
1548-7091
- Publication type
Article
- DOI
10.1038/nmeth.1706