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- Title
Sexually acquired severe acute hepatitis C infection in men who have sex with men.
- Authors
Wei, Sunny; Bogoch, Isaac I.; Dhalla, Irfan A.; Wong, David K.H.
- Abstract
In the natural history of infection, symptoms begin 3-4 weeks after exposure, but detectable sero-conversion with the appearance of anti-HCV IgG antibodies occurs around 8-11 weeks for most people.[3] Therefore, a negative anti-HCV antibody test early in the course of acute hepatitis does not rule out acute HCV infection. Acute infection with hepatitis C virus (HCV) is a cause of severe acute hepatitis. In acute HCV infection, testing by polymerase chain reaction (PCR) returns positive results, but results from tests of anti-HCV antibodies are typically negative for several weeks after exposure. Some public health laboratories allow for HCV PCR testing only if the anti-HCV antibody test result is positive, which can make diagnosing acute HCV infection challenging.
- Subjects
SYPHILIS; HEPATITIS C; GONORRHEA; MEDICAL personnel; INFECTION
- Publication
Canadian Medical Association Journal (CMAJ), 2022, Vol 194, Issue 45, pE1537
- Publication type
journal article
- DOI
10.1503/cmaj.220757