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- Title
Loss of p16[sup Ink4a] with retention of p19[Arf] predisposes mice to tumorigenesis.
- Authors
Sharpless, Norman E.; Bardeesy, Nabeel; Kee-Ho Lee; Carrasco, Daniel; Castrillon, Diego H.; Aguirre, Andrew J.; Wu, Emily A.; Horner, James W.; DePinho, Ronald A.
- Abstract
Describes the genetic factors which increase the predisposition of mice to tumorigenesis. Description of the generation and characterization of specific genes that retain normal function; Contrast to mouse embryo fibroblasts.
- Subjects
CARCINOGENESIS; TUMOR genetics
- Publication
Nature, 2001, Vol 413, Issue 6851, p86
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/35092592