We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance.
- Authors
Yang, Yiping; Huang, Ching-Tai; Huang, Xiaopei; Pardoll, Drew M.
- Abstract
One chief barrier to cancer immunotherapy is tumor-specific T cell tolerance. Here we compared the ability of hemagglutinin (HA)-encoding recombinant viruses versus 'HA-loaded' dendritic cells to reverse HA-specific CD8 tolerance and to protect mice
- Subjects
CANCER treatment; IMMUNOTHERAPY; T cells; CD antigens; GLYCOPROTEINS; LYMPHOCYTES
- Publication
Nature Immunology, 2004, Vol 5, Issue 5, p508
- ISSN
1529-2908
- Publication type
Article
- DOI
10.1038/ni1059