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- Title
Hormone levels in middle-aged and elderly men with and without erectile dysfunction in Taiwan.
- Authors
Hwang, T. I.-S.; Juang, G.-D.; Yeh, C.-H.; Chang, Y.-H.; Chou, K.-Y.; Chen, H.-E.
- Abstract
The change in sexual hormones with age in middle-aged and elderly Chinese men, with and without erectile dysfunction (ED), was investigated. Total testosterone (TT), free testosterone (FT), dehydroepiandrosterone sulfate (DHEAS), and sex hormone-binding globulin (SHBG) were determined from fasting serum samples by radioimmunoassay in 627 middle-aged and elderly ethnic Chinese men with and without ED. Calculated FT was derived from TT and SHBG. Patients with ED were subdivided into groups having low serum TT (<2.7 ng/ml) and normal TT (2.7 ng/ml). FT and DHEAS declined and SHBG rose with age in both normal patients and in patients with ED. TT and SHBG were lower in patients with ED than in normal subjects at all ages. In contrast to findings in previous studies, levels of FT were higher in patients with ED than in normal subjects. Hormonal changes in this Chinese population generally mirrored those in previously studied ethnic populations, except for higher FT in patients with ED. This suggests that hormonal levels in patients with ED may vary in different populations. The significance and reproducibility of this finding remains to be determined.International Journal of Impotence Research (2006) 18, 160–163. doi:10.1038/sj.ijir.3901382; published online 25 August 2005
- Subjects
SEX hormones; OLDER men; IMPOTENCE; ANDROGENS; BLOOD plasma
- Publication
International Journal of Impotence Research, 2006, Vol 18, Issue 2, p160
- ISSN
0955-9930
- Publication type
Article
- DOI
10.1038/sj.ijir.3901382