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- Title
Initiating Standardization in Fish Embryo Toxicity Assays.
- Authors
?tefania, ALĂMOREAN; ALBU, Cristian; CIOBAN, Roxana; MICLĂUŞ, Mădălina; SUCIU, Vasilena; OROIAN, Camelia Firuţa; PETRESCU-MAG, Ioan Valentin
- Abstract
Aquatic ecotoxicology, like ecotoxicology lato sensu, is a dynamic research field, based on laboratory experiments or field investigations and data collection. Such a research branch is important because it helps us understanding the level of toxicity of various chemical compounds used or proposed for use in agriculture and industry. After a review of the literature, we summarized in this paper the most recent trends in fish embryo toxicity assays. In the past, each researcher considered his own reasons to design the experimental protocol and chose the study animals. At present, these assays seem to harmonize under different but common standards elaborated by OECD, USEPA etc and, thus, common reference levels/values for studied chemicals are now available, making different results to be comparable and reproducible. OECD put the basis of embryo toxicity tests in three small fish species: zebrafish, Japanese medaka, and fathead minnow. Although there are many other fish species which demonstrated to be good models for research, the species number was limited to three in order to concentrate the information and standardize the protocols. Low number of model species and low number of protocols both mean high number of similar experiments which are comparable each other, and all these are comparable with OECD standard values.
- Subjects
FISH embryos; TOXICOLOGY of water pollution; POLLUTION; TOXICOLOGICAL chemistry; AGRICULTURAL chemicals
- Publication
ProEnvironment Promediu, 2015, Vol 8, Issue 24, p616
- ISSN
1844-6698
- Publication type
Article