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- Title
Antioxidant rich medicinal plants as a potential candidate to treat gastric ulcer.
- Authors
Altaf, Sidra; Abbas, Rao Zahid; Akhtar, Tayyaba; Siddique, Faisal; Mahmood, Muhammad Shahid; Khan, Muhammad Kasib; Ziaf, Khurram; Rafay, Muhammad; Khan, Muhammad Azam; Abbas, Asghar; ur Rehman, Tauseef; Marcelino, Liliana Aguilar; Zia, Muhammad; Khater, Hanem Fathy; Saeed, Nahla Muhammad; Abbasi, Karim Yar
- Abstract
Oxidative stress is a key cause of gastrointestinal disorders, primarily stomach ulcers. Multiple intrinsic and extrinsic mechanisms caused the body to produce reactive oxygen species (ROS). The body's antioxidant defense system protects against these reactive species. When the degree of ROS production exceeds the normal range, the body's natural defense system fails to neutralize these dangerous free radicals, necessitating need for an exogenous source of natural antioxidants. Natural herbal remedies have been widely employed as antioxidants to relieve oxidative stress in gastric ulcers. Polyphenols, tannins, essential oils, flavonoids, notably quercetin, carotenoids, vitamin C, vitamin A, and minerals are among the molecules of immense interest in bioassays due to their significant antioxidant effects. In the present review, several natural anti-ulcer medicinal plants along with their antioxidative mechanism have been reported. Electronic databases including PubMed, Google Scholar and Scopus were explored to identify the antioxidant and gastroprotective potential of all the plants.
- Subjects
STOMACH ulcers; MEDICINAL plants; VITAMIN A; REACTIVE oxygen species; ESSENTIAL oils; TANNINS; VITAMIN C
- Publication
Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, 2023, Vol 22, Issue 5, p560
- ISSN
0717-7917
- Publication type
Article
- DOI
10.37360/blacpma.23.22.5.41