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- Title
Effect of Systemic Hydrocortisone Initiated 7 to 14 Days After Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial.
- Authors
Halbmeijer, Nienke M.; Onland, Wes; Cools, Filip; Swarte, Renate; van der Heide-Jalving, Marja; Merkus, Maruschka P.; van Kaam, Anton H.; STOP-BPD Trial Collaborators
- Abstract
This follow-up to the STOP-BPD randomized clinical trial, which investigated the efficacy and safety of systemic hydrocortisone treatment initiated 7 to 14 days after birth in ventilator-dependent, very preterm infants in the Netherlands and Belgium at 36 weeks' postmenstrual age, examines the prespecified composite of death and neurodevelopmental impairment among these infants at 2 years' corrected age.
- Subjects
HYDROCORTISONE; DRUG efficacy; NEURODEVELOPMENTAL treatment for infants; DEVELOPMENT of premature infants; INFANT mortality; BRONCHOPULMONARY dysplasia; MORTALITY risk factors; CLINICAL trials; BRONCHOPULMONARY dysplasia prevention; PREMATURE infant diseases; RESEARCH; RESEARCH methodology; MEDICAL cooperation; EVALUATION research; ARTIFICIAL respiration; COMPARATIVE studies; LONGITUDINAL method
- Publication
JAMA: Journal of the American Medical Association, 2021, Vol 326, Issue 4, p355
- ISSN
0098-7484
- Publication type
journal article
- DOI
10.1001/jama.2021.9380