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Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice.
Published in:
PLoS Biology, 2016, v. 14, n. 4, p. 1, doi. 10.1371/journal.pbio.1002427
By:
- Murali, Sathish K.;
- Andrukhova, Olena;
- Clinkenbeard, Erica L.;
- White, Kenneth E.;
- Erben, Reinhold G.
Publication type:
Article
Generation of two multipotent mesenchymal progenitor cell lines capable of osteogenic, mature osteocyte, adipogenic, and chondrogenic differentiation.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02060-1
By:
- Prideaux, Matthew;
- Wright, Christian S.;
- Noonan, Megan L.;
- Yi, Xin;
- Clinkenbeard, Erica L.;
- Mevel, Elsa;
- Wheeler, Jonathan A.;
- Byers, Sharon;
- Wijenayaka, Asiri R.;
- Gronthos, Stan;
- Sankar, Uma;
- White, Kenneth E.;
- Atkins, Gerald J.;
- Thompson, William R.
Publication type:
Article
Circulating aKlotho influences phosphate handling by controlling FGF23 production.
Published in:
Journal of Clinical Investigation, 2012, v. 122, n. 12, p. 4710, doi. 10.1172/JCI64986
By:
- Smith, Rosamund C.;
- O'Bryan, Linda M.;
- bFarrow, Emily G.;
- Summers, Lelia J.;
- Clinkenbeard, Erica L.;
- Roberts, Jessica L.;
- Cass, Taryn A.;
- Saha, Joy;
- Broderick, Carol;
- Linda Ma, Y.;
- Qing Qiang Zeng;
- Kharitonenkov, Alexei;
- Wilson, Jonathan M.;
- Qianxu Guo;
- Haijun Sun;
- Allen, Matthew R.;
- Burr, David B.;
- Breyer, Matthew D.;
- White, Kenneth E.
Publication type:
Article
A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis.
Published in:
2007
By:
- Ichikawa, Shoji;
- Imel, Erik A.;
- Kreiter, Mary L.;
- Xijie Yu;
- MacKenzie, Donald S.;
- Sorenson, Andrea H.;
- Goetz, Regina;
- Mohammadi, Moosa;
- White, Kenneth E.;
- Econs, Michael J.;
- Yu, Xijie
Publication type:
journal article
Segregating the effects of ferric citrate‐mediated iron utilization and FGF23 in a mouse model of CKD.
Published in:
Physiological Reports, 2022, v. 10, n. 11, p. 1, doi. 10.14814/phy2.15307
By:
- Liesen, Michael P.;
- Noonan, Megan L.;
- Ni, Pu;
- Agoro, Rafiou;
- Hum, Julia M.;
- Clinkenbeard, Erica L.;
- Damrath, John G.;
- Wallace, Joseph M.;
- Swallow, Elizabeth A.;
- Allen, Matthew R.;
- White, Kenneth E.
Publication type:
Article
Erythropoietin and a hypoxia‐inducible factor prolyl hydroxylase inhibitor (HIF‐PHDi) lowers FGF23 in a model of chronic kidney disease (CKD).
Published in:
Physiological Reports, 2020, v. 8, n. 11, p. 1, doi. 10.14814/phy2.14434
By:
- Noonan, Megan L.;
- Clinkenbeard, Erica L.;
- Ni, Pu;
- Swallow, Elizabeth A.;
- Tippen, Samantha P.;
- Agoro, Rafiou;
- Allen, Matthew R.;
- White, Kenneth E.
Publication type:
Article
Hyperphosphatemic familial tumoral calcinosis: Response to acetazolamide and postulated mechanisms.
Published in:
American Journal of Medical Genetics. Part A, 2014, v. 164A, n. 6, p. 1545, doi. 10.1002/ajmg.a.36476
By:
- Finer, Gal;
- Price, Heather E.;
- Shore, Richard M.;
- White, Kenneth E.;
- Langman, Craig B.
Publication type:
Article
A case of Robin sequence, microgastria, radiohumeral synostosis, femoral deficiency, and other unusual findings: A newly recognized syndrome?
Published in:
American Journal of Medical Genetics. Part A, 2014, v. 164A, n. 2, p. 287, doi. 10.1002/ajmg.a.36273
By:
- Roberts, Jessica;
- Torres‐Martinez, Wilfredo;
- Farrow, Emily;
- Stevens, Abby;
- Delk, Paula;
- White, Kenneth E.;
- Weaver, David D.
Publication type:
Article
The pathophysiology of early-stage chronic kidney disease-mineral bone disorder (CKD-MBD) and response to phosphate binders in the rat.
Published in:
Journal of Bone & Mineral Research, 2011, v. 26, n. 11, p. 2672, doi. 10.1002/jbmr.485
By:
- Moe, Sharon M;
- Radcliffe, J Scott;
- White, Kenneth E;
- Gattone, Vincent H;
- Seifert, Mark F;
- Chen, Xianming;
- Aldridge, Blaire;
- Chen, Neal X
Publication type:
Article
Chloride Channel 7 (ClCN7) Gene Mutations and Autosomal Dominant Osteopetrosis, Type II.
Published in:
Journal of Bone & Mineral Research, 2003, v. 18, n. 8, p. 1513, doi. 10.1359/jbmr.2003.18.8.1513
By:
- Waguespack, Steven G;
- Koller, Daniel L;
- White, Kenneth E;
- Fishburn, Tonya;
- Carn, Gwenaelle;
- Buckwalter, Kenneth A;
- Johnson, Michelle;
- Kocisko, Maureen;
- Evans, Wayne E;
- Foroud, Tatiana;
- Econs, Michael J
Publication type:
Article
Na<sup>+</sup>/Ca<sup>2+</sup> exchange in rat osteoblast-like UMR 106 cells.
Published in:
Journal of Bone & Mineral Research, 1996, v. 11, n. 11, p. 1666, doi. 10.1002/jbmr.5650111110
By:
- White, Kenneth E.;
- Gesek, Frank A.;
- Friedman, Peter A.
Publication type:
Article
Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.
Published in:
Nature Genetics, 2006, v. 38, n. 11, p. 1310, doi. 10.1038/ng1905
By:
- Feng, Jian Q.;
- Ward, Leanne M.;
- Shiguang Liu;
- Yongbo Lu;
- Yixia Xie;
- Baozhi Yuan;
- Xijie Yu;
- Rauch, Frank;
- Davis, Siobhan I.;
- Shubin Zhang;
- Rios, Hector;
- Drezner, Marc K.;
- Quarles, L. Darryl;
- Bonewald, Lynda F.;
- White, Kenneth E.
Publication type:
Article
Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23.
Published in:
Nature Genetics, 2000, v. 26, n. 3, p. 345, doi. 10.1038/81664
By:
- White, Kenneth E.;
- Evans, Wayne E.;
- O'Riordan, Jeffery L.H.;
- Speer, Marcy C.;
- Econs, Michael J.;
- Lorenz-Depiereux, Bettina;
- Grabowski, Monika;
- Meitinger, Thomas;
- Strom, Tim M.
Publication type:
Article
Osteocyte Egln1/Phd2 links oxygen sensing and biomineralization via FGF23.
Published in:
Bone Research, 2023, v. 11, n. 1, p. 1, doi. 10.1038/s41413-022-00241-w
By:
- Noonan, Megan L.;
- Ni, Pu;
- Solis, Emmanuel;
- Marambio, Yamil G.;
- Agoro, Rafiou;
- Chu, Xiaona;
- Wang, Yue;
- Gao, Hongyu;
- Xuei, Xiaoling;
- Clinkenbeard, Erica L.;
- Jiang, Guanglong;
- Liu, Sheng;
- Stegen, Steve;
- Carmeliet, Geert;
- Thompson, William R.;
- Liu, Yunlong;
- Wan, Jun;
- White, Kenneth E.
Publication type:
Article
Osteocytic FGF23 and Its Kidney Function.
Published in:
Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.00592
By:
- Agoro, Rafiou;
- Ni, Pu;
- Noonan, Megan L.;
- White, Kenneth E.
Publication type:
Article
Hypophosphatemia with elevations in serum fibroblast growth factor 23 in a child with Jansen's metaphyseal chondrodysplasia.
Published in:
2009
By:
- Brown, Whitney W;
- Jüppner, Harald;
- Langman, Craig B;
- Price, Heather;
- Farrow, Emily G;
- White, Kenneth E;
- McCormick, Kenneth L
Publication type:
journal article
The Role of Mutant UDP-N-Acetyl-α-D-Galactosamine-Polypeptide N-Acetylgalactosaminyltransferase 3 in Regulating Serum Intact Fibroblast Growth Factor 23 and Matrix Extracellular Phosphoglycoprotein in Heritable Tumoral Calcinosis.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 10, p. 4037, doi. 10.1210/jc.2006-0305
By:
- Garringer, Holly J.;
- Fisher, Corinne;
- Larsson, Tobias E.;
- Davis, Siobhan I.;
- Koller, Daniel L.;
- Cullen, Michael J.;
- Draman, Mohamad S.;
- Conlon, Niamh;
- Jain, Alka;
- Fedarko, Neal S.;
- Dasgupta, Bhaskar;
- White, Kenneth E.
Publication type:
Article
A Novel Recessive Mutation in Fibroblast Growth Factor-23 Causes Familial Tumoral Calcinosis.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 4, p. 2424, doi. 10.1210/jc.2004-2238
By:
- Larsson, Tobias;
- Xijie Yu;
- Davis, Siobhan I.;
- Draman, Mohamad S.;
- Mooney, Sean D.;
- Cullen, Michael J.;
- White, Kenneth E.
Publication type:
Article
Measurement of Tartrate-Resistant Acid Phosphatase and the Brain Isoenzyme of Creatine Kinase Accurately Diagnoses Type II Autosomal Dominant Osteopetrosis but Does Not Identify Gene Carriers.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 5, p. 2212, doi. 10.1210/jcem.87.5.8497
By:
- WAGUESPACK, STEVEN G.;
- HUI, SIU L.;
- WHITE, KENNETH E.;
- BUCKWALTER, KENNETH A.;
- ECONS, MICHAEL J.
Publication type:
Article
The autosomal dominant hypophosphatemic rickets (ADHR) gene Is a secreted olpypeptide overexpressed by Tumors that cause phosphate wasting.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 2, p. 497, doi. 10.1210/jcem.86.2.7408
By:
- WHITE, KENNETH E.;
- JONSSON, KENNETH B.;
- CARN, GWENAELLE;
- HAMPSON, GEETA;
- SPECTOR, TIM D.;
- MANNSTADT, MICHAEL;
- LORENZ-DEPIEREUX, BETTINA;
- AKIMITSU MIYAUCHI;
- IN MYUNG YANG;
- LJUNGGREN, ÖSTEN;
- MEITINGER, THOMAS;
- STROM, TIM M.;
- JÜPPNER, HARALD;
- ECONS, MICHAEL J.
Publication type:
Article
Locus Heterogeneity of Autosomal Dominant Osteopetrosis (ADO).
Published in:
Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 3, p. 1047, doi. 10.1210/jcem.84.3.5578
By:
- WHITE, KENNETH E.;
- KOLLER, DANIEL L.;
- TAKACS, ISTVAN;
- BUCKWALTER, KENNETH A.;
- FOROUD, TATIANA;
- ECONS, MICHAEL J.
Publication type:
Article
Gabapentin Disrupts Binding of Perlecan to the α 2 δ 1 Voltage Sensitive Calcium Channel Subunit and Impairs Skeletal Mechanosensation.
Published in:
Biomolecules (2218-273X), 2022, v. 12, n. 12, p. 1857, doi. 10.3390/biom12121857
By:
- Reyes Fernandez, Perla C.;
- Wright, Christian S.;
- Masterson, Adrianna N.;
- Yi, Xin;
- Tellman, Tristen V.;
- Bonteanu, Andrei;
- Rust, Katie;
- Noonan, Megan L.;
- White, Kenneth E.;
- Lewis, Karl J.;
- Sankar, Uma;
- Hum, Julia M.;
- Bix, Gregory;
- Wu, Danielle;
- Robling, Alexander G.;
- Sardar, Rajesh;
- Farach-Carson, Mary C.;
- Thompson, William R.
Publication type:
Article
Pharmacological management of X‐linked hypophosphataemia.
Published in:
British Journal of Clinical Pharmacology, 2019, v. 85, n. 6, p. 1188, doi. 10.1111/bcp.13763
By:
- Imel, Erik A.;
- White, Kenneth E.
Publication type:
Article
Hypophosphatemic Rickets in Opsismodysplasia.
Published in:
Journal of Pediatric Endocrinology & Metabolism, 2007, v. 20, n. 1, p. 79
By:
- Zeger, Martha Dechert;
- Adkins, Deanna;
- Fordham, Lynn A.;
- White, Kenneth E.;
- Schoenau, Eckhard;
- Rauch, Frank;
- Loechner, Karen J.
Publication type:
Article
The pathophysiology of the chronic kidney disease-mineral bone disorder: synopsis of a symposium at the Sun Valley Musculoskeletal Biology Workshop.
Published in:
IBMS BoneKEy, 2013, v. 10, n. 11, p. 444, doi. 10.1038/bonekey.2013.178
By:
- Hruska, Keith A;
- Leonard, Mary;
- Pereira, Renata;
- White, Kenneth E;
- Moe, Orson W
Publication type:
Article
Single cell cortical bone transcriptomics define novel osteolineage gene sets altered in chronic kidney disease.
Published in:
Frontiers in Endocrinology, 2023, v. 14, p. 1, doi. 10.3389/fendo.2023.1063083
By:
- Agoro, Rafiou;
- Nookaew, Intawat;
- Noonan, Megan L.;
- Marambio, Yamil G.;
- Sheng Liu;
- Wennan Chang;
- Hongyu Gao;
- Hibbard, Lainey M.;
- Metzger, Corinne E.;
- Horan, Daniel;
- Thompson, William R.;
- Xiaoling Xuei;
- Yunlong Liu;
- Chi Zhang;
- Robling, Alexander G.;
- Bonewald, Lynda F.;
- Wan, Jun;
- White, Kenneth E.
Publication type:
Article
The HIF‐PHI BAY 85‐3934 (Molidustat) Improves Anemia and Is Associated With Reduced Levels of Circulating FGF23 in a CKD Mouse Model.
Published in:
Journal of Bone & Mineral Research, 2021, v. 36, n. 6, p. 1117, doi. 10.1002/jbmr.4272
By:
- Noonan, Megan L;
- Ni, Pu;
- Agoro, Rafiou;
- Sacks, Spencer A;
- Swallow, Elizabeth A;
- Wheeler, Jonathan A;
- Clinkenbeard, Erica L;
- Capitano, Maegan L;
- Prideaux, Matthew;
- Atkins, Gerald J;
- Thompson, William R;
- Allen, Matthew R;
- Broxmeyer, Hal E;
- White, Kenneth E
Publication type:
Article
Phenotypic and Genotypic Characterization and Treatment of a Cohort With Familial Tumoral Calcinosis/Hyperostosis-Hyperphosphatemia Syndrome.
Published in:
Journal of Bone & Mineral Research, 2016, v. 31, n. 10, p. 1845, doi. 10.1002/jbmr.2870
By:
- Ramnitz, Mary Scott;
- Gourh, Pravitt;
- Goldbach-Mansky, Raphaela;
- Wodajo, Felasfa;
- Ichikawa, Shoji;
- Econs, Michael J;
- White, Kenneth E;
- Molinolo, Alfredo;
- Chen, Marcus Y;
- Heller, Theo;
- Del Rivero, Jaydira;
- Seo-Mayer, Patricia;
- Arabshahi, Bita;
- Jackson, Malaka B;
- Hatab, Sarah;
- McCarthy, Edward;
- Guthrie, Lori C;
- Brillante, Beth A;
- Gafni, Rachel I;
- Collins, Michael T
Publication type:
Article
Conditional Deletion of Murine Fgf23: Interruption of the Normal Skeletal Responses to Phosphate Challenge and Rescue of Genetic Hypophosphatemia.
Published in:
Journal of Bone & Mineral Research, 2016, v. 31, n. 6, p. 1247, doi. 10.1002/jbmr.2792
By:
- Clinkenbeard, Erica L;
- Cass, Taryn A;
- Ni, Pu;
- Hum, Julia M;
- Bellido, Teresita;
- Allen, Matthew R;
- White, Kenneth E
Publication type:
Article
Neonatal Iron Deficiency Causes Abnormal Phosphate Metabolism by Elevating FGF23 in Normal and ADHR Mice.
Published in:
Journal of Bone & Mineral Research, 2014, v. 29, n. 2, p. 361, doi. 10.1002/jbmr.2049
By:
- Clinkenbeard, Erica L;
- Farrow, Emily G;
- Summers, Lelia J;
- Cass, Taryn A;
- Roberts, Jessica L;
- Bayt, Christine A;
- Lahm, Tim;
- Albrecht, Marjorie;
- Allen, Matthew R;
- Peacock, Munro;
- White, Kenneth E
Publication type:
Article
Fibroblast Growth Factor 23 and Its Receptors.
Published in:
Therapeutic Apheresis & Dialysis, 2005, v. 9, n. 4, p. 308, doi. 10.1111/j.1744-9987.2005.00287.x
By:
- Xijie Yu;
- White, Kenneth E
Publication type:
Article
Letters to the Editors: 1.
Published in:
Clinical Endocrinology, 2003, v. 58, n. 6, p. 795, doi. 10.1046/j.1365-2265.2003.18021.x
By:
- Hoogendoorn, Elizabeth H.;
- White, Kenneth E.;
- Econs, Michael J.;
- Hermus, Ad R.
Publication type:
Article
A rat model of chronic kidney disease-mineral bone disorder.
Published in:
Kidney International, 2009, v. 75, n. 2, p. 176, doi. 10.1038/ki.2008.456
By:
- Moe, Sharon M.;
- Chen, Neal X.;
- Seifert, Mark F.;
- Sinders, Rachel M.;
- Duan, Dana;
- Xianming Chen;
- Yun Liang;
- Radcliff, J. Scott;
- White, Kenneth E.;
- Gattone, Vincent H.
Publication type:
Article
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23.
Published in:
Kidney International, 2001, v. 60, n. 6, p. 2079, doi. 10.1046/j.1523-1755.2001.00064.x
By:
- White, Kenneth E.;
- Carn, Gwenaelle;
- Lorenz-Depiereux, Bettina;
- Benet-Pages, Anna;
- Strom, Tim M.;
- Econs, Michael J.
Publication type:
Article
NCX1 Na/Ca exchanger inhibition by antisense oligonucleotides in mouse distal convoluted tubule cells.
Published in:
Kidney International, 1998, v. 54, n. 3, p. 897, doi. 10.1046/j.1523-1755.1998.00056.x
By:
- White, Kenneth E.;
- Gesek, Frank A.;
- Reilly, Robert F.;
- Friedman, Peter A.
Publication type:
Article

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