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- Title
FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases.
- Authors
De Vos, Filip Y. F. L.; Mulder, Sasja F.; Drenth, Joost P. H.; Nagtegaal, Iris D.; Fütterer, Jurgen J.; van der Graaf, Winette T. A.
- Abstract
<bold>Background: </bold>Bleomycin has become an integral part of chemotherapy in patients with germ-cell tumors. One of the most feared side effects is bleomycin-induced pneumonitis. In patients with mild or moderate BIP, radiological signs disappear almost completely within nine months after discontinuation of bleomycin treatment.<bold>Case Presentation: </bold>We present a patient with a history of non seminoma of the testis and bleomycin-induced pneumonitis. During follow-up, regression of the hypothesis of eosinophilic migration to the liver after regression of bleomycin-induced pneumonitis is highly suspicious based on transient eosinophilia and focal eosinophilic liver disease.<bold>Conclusion: </bold>As follow up may consist of CT scanning in germ-line tumor patients, transient eosinophilic liver lesions reported during regressive bleomycin-induced pneumonitis should not be presumed automatically as metastatic tumor relapse and require further sequential imaging and pathological examination.
- Subjects
PNEUMONIA; BLEOMYCIN; DRUG side effects; COMPUTED tomography; METASTASIS; THERAPEUTICS
- Publication
BMC Cancer, 2013, Vol 13, Issue 1, p1
- ISSN
1471-2407
- Publication type
journal article
- DOI
10.1186/1471-2407-13-491