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- Title
Clinical effects of sitting bath with different concentrations of sodium chloride solution combined with 0.1% metronidazole on perianal infection of leukemia patients.
- Authors
YAO Xiaodan; WANG Li; DING Ting; FU Adan; XU Liwen
- Abstract
Objective: To explore the clinical effects of siting bath with different concentrations sodium chloride solution combined with 0.1% metronidazole on perianal infection in patients with leukemia. Methods: A total of 202 patients in Hematology department of our hospital from June 2010 to May 2018, were randomly divided into experiment 1 group(41 patients), experiment 2 group(42 cases), experiment 3 groups(40 cases), control 1 group(39 cases)and control 2 group(40 cases). Patients in experiment 1 group, experiment 2 group, experiment 3 group received siting bath with 0.9% sodium chloride solution, 1.6% sodium chloride solution, and 3.0% sodium chloride solution respectively, combined with 0.1% metronidazole injection. Patients in control 1 group received siting bath with 0.1% metronidazole solution. Patients in control 2 group received siting bath with potassium permanganate solution. The therapeutic effects of perianal infection of 5 groups was compared.Results: The therapeutic effects of experiment 2 group and 3 group were better than that of control 1 group. The therapeutic effects of experiment 2 group and 3 group were better than that of control 2 group. The therapeutic effects of experiment 2 group and 3 group were better than that of experiment 1 group. The therapeutic effect of experiment 2 group was better than that of experiment 3 group(all P<0.05). Conclusion: The therapeutic effects of siting bath with 1.6% sodium chloride solution and 3.0% sodium chloride solution combined with 0.1% metronidazole injection were better than that sitz bath with 0.1% metronidazole solution or potassium permanganate solution alone. What's more, the effect of 1.6% sodium chloride solution combined with 0.1% metronidazole injection was the best for perianal infection.
- Subjects
HALOTHERAPY; BATHS; CANCER patients; LEUKEMIA; METRONIDAZOLE; PERINEUM; STATISTICAL sampling; SITTING position; STERILIZATION (Disinfection); WOUND infections; RANDOMIZED controlled trials; DESCRIPTIVE statistics
- Publication
Chinese Nursing Research, 2020, Vol 34, Issue 6, p1057
- ISSN
1009-6493
- Publication type
Article
- DOI
10.12102/j.issn.1009-6493.2020.06.030